手足口病治疗中施保利通联合干扰素的应用分析  

Application Analysis of Esberitox Combined with Interferon in the Treatment of Hand-foot-mouth Disease

作　　者：邬吉伟 温伟溪 王慧娟[1] WU Jiwei;WEN Weixi;WANG Huijuan(Shenzhen Longgang Central Hospital,Shenzhen 518100,China)

机构地区：[1]深圳市龙岗中心医院,广东深圳518100

出　　处：《中外医学研究》2021年第7期147-149,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:研究手足口病治疗中施保利通联合干扰素的应用效果。方法:研究对象为2019年1月-2020年1月入院的82例手足口病患儿,参考随机数字表法划分为两组,分别为对照组与研究组,每组41例;对照组单用干扰素治疗,研究组联用施保利通与干扰素治疗。比较两组治疗前后血浆免疫球蛋白(免疫球蛋白A、免疫球蛋白G、免疫球蛋白M)水平、血清炎性因子(白细胞介素-10、白细胞介素-6、白细胞介素-1β)水平与治疗后总有效率。结果:研究组较对照组治疗后血浆免疫球蛋白水平更高,血清炎性因子水平更低,总有效率更高(P<0.05)。结论:手足口病治疗中施保利通联合干扰素的应用效果显著,可增强患儿机体免疫力,降低炎性因子水平,促使其快速康复。Objective:To study the application effect of Esberitox combined with Interferon in the treatment of hand-foot-mouth disease(HFMD).Method:A total of 82 children with HFMD admitted from January 2019 to January 2020 were divided into the control group and the study group according to the random number table method,with 41 cases in each group.The control group was treated with interferon alone,and the study group was treated with Esberitox and Interferon.The plasma immunoglobulins(immunoglobulin A,immunoglobulin G,immunoglobulin M)in the two groups before and after treatment were compared.The levels of serum inflammatory factors(IL-10,IL-6,IL-1β)and the total effective rate after treatment.Result:Compared with the control group,the study group had higher plasma immunoglobulin level,lower serum inflammatory factor level and higher total effective rate,the differences were statistically significant(P<0.05).Conclusion:In the treatment of hand-foot-mouth disease,the application effect of Esberitox combined with Interferon is significant,which can enhance the immunity of children,reduce the level of inflammatory factors,and promote their rapid recovery.

关 键 词：手足口病 施保利通 干扰素 免疫球蛋白 炎性因子 

分 类 号：R725.1[医药卫生—儿科]