非编码RNA在肌肉生长发育中的调控作用研究进展  

Research Progress Regulation of Non-coding RNAs in Muscle Growth and Development

作　　者：张朋朋 王亚玲[1] 韩秋 程晓芳 李岑岑 徐海霞[1] 徐永杰[1] ZHANG Pengpeng;WANG Yaling;HAN Qiu;CHENG Xiaofang;LI Cencen;XU Haixia;XU Yongjie(College of Life Sciences,Xinyang Normal University,Xinyang 464000,China)

机构地区：[1]信阳师范学院生命科学学院,河南信阳464000

出　　处：《信阳师范学院学报（自然科学版）》2021年第2期339-344,共6页Journal of Xinyang Normal University(Natural Science Edition)

基　　金：国家自然科学基金项目(31601167,31972537);河南省重大科技专项项目(201300111200);河南省高等学校重点科研项目(21A230017)。

摘　　要：非编码RNA(noncoding RNA,ncRNA)在肌肉生长发育过程中发挥着重要的作用,参与调控骨骼肌干细胞的增殖、分化和肌纤维的肥大等过程.利用30篇文献综述了3类非编码RNA(长链非编码RNA、miRNA和环状RNA)在骨骼肌生长发育中的最新研究进展,旨在为肌肉疾病的治疗和农业动物生产性能的改良提供新思路.Noncoding RNA(ncRNA),which plays an important role in the process of muscle growth and development,involves in skeletal muscle stem cells proliferation,differentiation and muscle fibers hypertrophy.In this article,30 literatures were used to review the latest research progress of three types of non-coding RNAs(long non-coding RNAs,miRNAs and circular RNAs)in skeletal muscle growth and development,in order to provide new ideas to the treatment of muscle diseases and the improvement of farm animal growthperformance.

关 键 词：肌肉发育 长链非编码RNA MIRNA 环状RNA 

分 类 号：S852[农业科学—基础兽医学]