原发性免疫性血小板减少症儿童生活质量及其影响因素研究进展  

Quality of life of children with primary immune thrombocytopenia and its influencing factors

作　　者：张姮 魏宇婷 方拥军[1] ZHANG Heng;WEI Yu-ting;FANG Yong-jun(Department of Hematology and Oncology,Children’s Hospital of Nanjing Medical University,Nanjing 210008,China)

机构地区：[1]南京医科大学附属儿童医院血液肿瘤科,江苏南京210008

出　　处：《中国实用儿科杂志》2021年第2期99-103,共5页Chinese Journal of Practical Pediatrics

摘　　要：原发性免疫性血小板减少症(primary immune thrombocytopenia,ITP)是儿童最常见的出血性疾病,常表现为皮肤和黏膜出血,罕见颅内出血。儿童ITP为急性自限性疾病,大多数出血倾向重但预后良好;少数迁延反复,呈慢性趋势。尽管儿童ITP严重出血风险低,但慢性ITP血小板计数反复减少常引起家属的担忧,故患儿的日常活动常会受到限制。此外,治疗药物引起的相关不良反应、对病程迁延及疾病预后的担忧等都会影响到患儿的健康及相关生活质量。该文主要针对ITP儿童的生活质量及主要影响因素研究进展展开论述。Primary immune thrombocytopenia(ITP)is the most common hemorrhagic disease in children. The most common clinical manifestation of ITP is skin and mucosal hemorrhage,and the intracranial hemorrhage is relatively rare. ITP in children is mostly a acute self-limited disease. Most patients have higher bleeding tendency but good prognosis,and a few of them are chronic with repeated delay. Although children with ITP are at low risk of severe bleeding,repeated decrease of platelet count is a common cause of concern in the family,resulting in limited daily activities of children.In addition,the adverse reactions associated with therapeutic drugs,the course of the disease and the concern about the prognosis of ITP will affect the children’s health-related quality of life. This paper mainly discusses the research progress of health-related quality of life in children with ITP and the main influencing factors.

关 键 词：原发性免疫性血小板减少症 健康相关生活质量 儿童 

分 类 号：R72[医药卫生—儿科]