6932例患者泌尿生殖道沙眼衣原体与淋病奈瑟菌感染调查分析  

Investigation and analysis of Chlamydia trachomatis and Neisseria gonorrhoeae infection of urogenital tract in 6932 patients

作　　者：蒋燕成[1] 张建明 陈辉华[1] 陈紫萱[1] 张志珊[1] JIANG Yancheng;ZHANG Jianming;CHEN Huihua;CHEN Zixuan;ZHANG Zhishan(Department of Clinical Laboratory,Quanzhou First Hospital Affiliated to Fujian Medical University,Quanzhou,Fujian 362000,China)

机构地区：[1]福建医科大学附属泉州第一医院检验科,福建泉州362000

出　　处：《检验医学与临床》2021年第7期941-944,共4页Laboratory Medicine and Clinic

摘　　要：目的了解泉州地区人群泌尿生殖道沙眼衣原体(CT)和淋病奈瑟菌(NG)临床感染现状,为临床诊断治疗提供参考。方法选取2019年9月至2020年3月在该院泌尿科、妇产科、皮肤性病科就诊的患者6932例,其中男性患者1320例,女性患者5612例。采用荧光定量聚合酶链反应检测患者泌尿生殖道的CT和NG。结果6932例患者CT和NG阳性率分别为8.98%和6.85%,二者同时检出患者达1.60%。男性患者CT和NG阳性率分别为3.48%和4.95%,二者同时检出患者占1.11%;女性患者CT和NG阳性率分别为5.50%和1.90%,二者同时检出患者占0.49%。男性NG感染率(4.95%)显著高于女性(1.90%),差异有统计学意义(P<0.05);而男性CT感染率(3.48%)低于女性(5.50%),差异有统计学意义(P<0.05)。从年龄分布来看,以20~30岁年龄段2种病原体感染率最高。结论泉州地区泌尿生殖道CT、NG感染率不尽相同,该地区男性患者NG感染率高于女性,而女性患者CT感染率高于男性,CT、NG同时感染在男性患者中较为常见,20~30岁年龄段感染率最高,应该加强监测。Objective To investigate the clinical infection status of Chlamydia trachomatis(CT)and Neisseria gonorrhoeae(NG)in genitourinary tract of population in Quanzhou,and to provide reference for clinical diagnosis and treatment.Methods A total of 6932 patients admitted to the Department of Urology,Obstetrics and Gynecology,Dermatology and Venereology of our hospital from September 2019 to March 2020 were selected,including 1320 male patients and 5612 female patients.CT and NG of the urogenital tract were detected by fluorescence quantitative PCR,and the results were analyzed.Results The positive rates of CT and NG in 6932 patients were 8.98%and 6.85%,respectively,and 1.60%were both detected simultaneously.The positive rates of CT and NG in male patients were 3.48%and 4.95%,respectively,and 1.11%were both detected simultaneously.The positive rates of CT and NG in female patients were 5.50%and 1.90%,respectively,and 0.49%of the patients were detected with both.The NG infection rate of male(4.95%)was significantly higher than that of female(1.90%),and the difference was statistically significant(P<0.05).The CT infection rate of male(3.48%)was lower than that of female(5.50%),and the difference was statistically significant(P<0.05).In terms of age distribution,the infection rate of the two pathogens was highest in the age group of 20-30 years old.Conclusion The CT and NG infection rates of urogenital tract in Quanzhou area are different.The NG infection rate of male patients is higher than that of female patients in this area,while the CT infection rate of female patients is higher than that of male patients.Meanwhile,the simultaneous infection of CT and NG is more common in male patients,and the infection rate of 20-30 years old group is the highest,so monitoring should be strengthened.

关 键 词：沙眼衣原体 淋病奈瑟菌 聚合酶链反应 性传播疾病 

分 类 号：R446.5[医药卫生—诊断学]