不同疗法治疗下肢深静脉瓣膜功能不全伴Cockett综合征的效果探讨  

Different therapies for deep vein valve insufficiency of lower extremity associated with Cockett syndrome: comparison of curative effect

作　　者：郑世宾 郭衍 秦金保[2] 吴超 李维敏[2] 张宏中 沈建东[3] ZHENG Shibin;GUO Yan;QIN Jinbao;WU Cao;LI Weimin;ZHANG Hongzhong;SHEN Jiandong(Department of Vascular Surgery,Junan County People’s Hospital,Junan County,Shandong Province 276600,China)

机构地区：[1]莒南县人民医院血管外科,276600 [2]上海交通大学医学院附属第九人民医院血管外科 [3]江苏南通市第三人民医院介入血管科

出　　处：《介入放射学杂志》2021年第2期173-177,共5页Journal of Interventional Radiology

基　　金：江苏省南通市科技局科研基金(MS12017017-2)。

摘　　要：目的探讨不同联合治疗方法对下肢深静脉瓣膜功能不全伴Cockett综合征的疗效。方法回顾性分析2016年6月至2018年6月上海市第九人民医院收治的120例左下肢深静脉瓣膜功能不全伴Cockett综合征患者临床资料。患者分为两组,A组(n=60)单纯行大隐静脉(GSV)高位结扎+静脉腔内激光治疗(EVLT)+硬化剂治疗,B组(n=60)行髂静脉支架植入术后再行GSV高扎+EVLT+硬化剂治疗。结果 A、B组技术成功率均为100%。术后随访6~24个月,平均12个月。A组19例(31.7%)有不同程度患肢肿胀,7例(11.7%)色素沉着,4例(6.7%)足踝区溃疡形成,2例(3.3%)继发下肢深静脉血栓形成(DVT);B组有2例(3.3%)患肢轻度肿胀,保守治疗后缓解。结论 GSV高位结扎+EVLT+硬化剂注射联合髂静脉球囊扩张和支架植入术治疗下肢深静脉瓣膜功能不全伴Cockett综合征效果确切,微创安全。Objective To discuss the curative effect of different therapies in treating deep vein valve insufficiency of lower extremity associated with Cockett syndrome. Methods The clinical data of 120 patients with deep vein valve insufficiency of lower extremity complicated by Cockett syndrome, who were admitted to the Shanghai Ninth People’s Hospital of China during the period from June 2016 to June 2018 to receive treatment, were retrospective analyzed. The patients were divided into group A(n=60) and group B(n=60).The patients of group A received high ligation of great saphenous vein(GSV), endovenous laser treatment(EVLT) and sclerosing agent injection, while the patients of group B received iliac vein stent implantation followed by high ligation of GSV,EVLT and sclerosing agent injection. Results In both groups the technical success rate was 100%. The patients were followed up for 6-24 months with a mean of 12 months. In group A,19 patients(31.7%) developed different degrees of swelling of the affected limbs, 7 patients(11.7%) had pigmentation, and 4 patients(6.7%) showed ulcer formation in ankle area, 2 patients(3.3%) developed deep vein thrombosis(DVT) of lower extremity. In group B, 2 patients(3.3%) developed mild swelling of the affected limbs, which was relieved after conservative treatment. Conclusion For the treatment of deep vein valve insufficiency of lower extremity associated with Cockett syndrome, high ligation of GSV together with EVLT,sclerosing agent injection and iliac vein balloon dilatation plus stenting is minimally-invasive and safe with reliable curative effect.

关 键 词：下肢深静脉瓣膜功能不全 COCKETT综合征 腔内治疗 微创治疗 

分 类 号：R622.4[医药卫生—整形外科]