细银质针导热松解联合臭氧注射与神经根脉冲射频治疗带状疱疹后神经痛的疗效比较  

Comparison of the efficacy of thin silver needle heat conduction combined with ozone injection and nerve root pulsed radiofrequency in the treatment of postherpetic neuralgia

作　　者：张媛婧 樊碧发[2] 刘星 张毅[2] 李怡帆 王新星 王泊宁 毛鹏[2] ZHANG Yuan-Jing;FAN Bi-Fa;LIU Xing;ZHANG Yi;LI Yi-Fan;WANG Xin-Xing;WANG Bo-Ning;MAO Peng(Department of Graduate School,Beijing University of Chinese Medicine,Beijing 100029,China;Department of Pain Medicine,China-Japan Friendship Hospital,Beijing 100029,China)

机构地区：[1]北京中医药大学研究生院,北京100029 [2]中日友好医院疼痛科,北京100029

出　　处：《中国疼痛医学杂志》2021年第3期196-201,共6页Chinese Journal of Pain Medicine

基　　金：国家临床重点专科建设项目(2014-zdzk-002)。

摘　　要：目的:探讨细银质针导热松解联合臭氧注射与神经根脉冲射频治疗带状疱疹后神经痛(postherpetic neuralgia,PHN)的疗效。方法:选择中日友好医院疼痛科2018年1月至2019年11月PHN病人80例,随机均分为细银质针导热松解联合臭氧注射组(S组)和神经根脉冲射频组(R组)。观察术前、术后1小时、3个月、6个月的视觉模拟评分法(visual analogue scale,VAS)评分、阿森斯失眠量表(Athens insomnia scale,AIS)评分、生活质量指数问卷(quality of life index,QL-index)评分和总体疗效。结果:两组病人术前VAS、AIS和QL-index评分无统计学差异,术后1小时、3个月和6个月,两组的VAS和AIS评分均明显低于术前基础值,且QL-index评分明显高于术前基础值(P<0.01)。两组术后1小时的VAS和AIS评分无统计学差异,但术后3个月、6个月时S组明显低于R组(P<0.05)。两组QL-index评分和总体有效率在各时间点无统计学差异。结论:细银质针导热松解联合臭氧注射和神经根脉冲射频均可有效治疗PHN,但细银质针导热松解联合臭氧注射的痊愈率更高。Objective:To compare the efficacy of thin silver needle heat conduction combined with ozone injection and nerve root pulsed radiofrequency in the treatment of postherpetic neuralgia(PHN).Methods:Eighty patients with PHN from January 2018 to November 2019 in the Pain Department of China-Japan Friendship Hospital were selected and randomly equally allocated to thin silver needle heat conduction combined with ozone injection group(group S)and nerve root pulsed radiofrequency group(group R).Visual analogue scale(VAS),Athens insomnia scale(AIS),Quality of life index(QL-index)and overall efficacy were observed before and 1 hour,3 months and 6 months after operation.Results:The VAS,AIS,and QL-index scores were not statistically different between the two groups before operation.At 1 hour,3 months and 6 months after operation,VAS and AIS scores of the two groups were significantly lower than those before operation,and QL index scores of the two groups were significantly higher than those before operation(P<0.01).There was no significant difference in VAS and AIS scores between the two groups at 1 h after operation,but the VAS and AIS scores in Group S were significantly lower than those in Group R at 3 and 6 months after operation(P<0.05).There was no statistical differences in QL-index score and overall efficacy between the two groups at each time point.Conclusion:Thin silver needle heat conduction combined with ozone injection and nerve root pulsed radiofrequency are both effective in the treatment of PHN,but the former has a higher cure rate.

关 键 词：带状疱疹后神经痛 细银质针导热松解 臭氧注射 神经根脉冲射频 神经病理性疼痛 

分 类 号：R752.12[医药卫生—皮肤病学与性病学]