氧气为唯一氧化剂的交叉脱氢偶联反应研究进展  

Recent Advances in Cross-Dehydrogenative-Coupling Reactions Using Molecular Oxygen as the Sole Oxidant

作　　者：庄伟辉 张晓凤[1] 黄秋锋[1,2] Zhuang Weihui;Zhang Xiaofeng;Huang Qiufeng(College of Chemistry&Materials Science,Fujian Normal University,Fuzhou 350007;Key Laboratory of Polymer Materials of Fujian Province,Fuzhou 350007)

机构地区：[1]福建师范大学化学与材料学院,福州350007 [2]福建省高分子材料重点实验室,福州350007

出　　处：《有机化学》2021年第2期529-542,共14页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(No.21872028);福建省教育厅青年重点基金(No.JZ160424);福建省高校新世纪人才基金资助项目。

摘　　要：脱氢偶联反应是最有效、最直接的构建C-C键或C-杂键的一种方法.但是目前大多数脱氢偶联反应需要使用化学计量的有毒氧化剂,如PhI(OAc)_(2)、苯醌、Cu(Ⅱ)盐、有机过氧酸或Ag(Ⅰ)盐等.氧气廉价易得,作为脱氢偶联反应中的唯一氧化剂,副产物只有水,不会产生其他有毒副产物,是绿色环境友好的方法.根据催化剂的分类,综述了氧气作为唯一氧化剂的交叉脱氢偶联反应研究进展.Cross-dehydrogenative-coupling(CDC) reactions have emerged as one of the most efficient and straightforward methods for the formation of C-C bonds or C-heteroatom bonds. However, most CDC reactions require hazardous and stoichiometric oxidants, such as PhI(OAc)_(2), benzoquinone, copper(Ⅱ) salts, organic peroxide acid and silver(Ⅰ) salts. A green and environmentary benign approach is using molecular oxygen(O2) as oxidant in the reactions, which usually form water as by-product. According to the classification of catalysts, the research progress of cross dehydrogenation coupling reaction with oxygen as the only oxidant is reviewed.

关 键 词：交叉脱氢偶联 氧气 唯一氧化剂 

分 类 号：O621.251[理学—有机化学]