精准医疗时代下生物样本库的建设与发展特点  

The Characteristics of the Construction and Development of Biobank in the Era of Precision Medicine

作　　者：刘艳红[1,2] 叶庆 LIU Yan-hong;YE Qing(Department of Pathology,The Affiliated Hospital of Nanjing University Medical School,Nanjing 210008,China;Biobank,Nanjing Drum Tower Hospital,The Affiliated Hospital of Nanjing University Medical School,Nanjing 210008,China;Department of Pathology,The First Affiliated Hospital of University of Science and Technology of China,Hefei 230036,China;Intelligent Pathology Institute,The First Affiliated Hospital of University of Science and Technology of China,Hefei 230036,China)

机构地区：[1]南京大学医学院附属鼓楼医院病理科,南京210008 [2]南京大学医学院附属鼓楼医院生物样本库,南京210008 [3]中国科学技术大学附属第一医院临床病理中心,合肥230036 [4]中国科学技术大学附属第一医院智慧病理学研究所,合肥230036

出　　处：《协和医学杂志》2021年第2期254-259,共6页Medical Journal of Peking Union Medical College Hospital

基　　金：江苏省重大疾病生物资源样本库妇产疾病子库(BM2015004);江苏省重大疾病生物资源样本库开放课题(SBK202006001,SBK202006002,SBK202006003)

摘　　要：近年来,在"健康中国"大背景下,精准医疗和生物样本库迎来了快速发展的黄金时期。精准医疗时代,生物样本库作为医疗行业的新兴领域,有其自身发展趋势和特点,表现为发展进程需标准化和规范化、高度依赖信息化建设、离不开多中心联盟和资源共享、需多学科融合支撑等。随着精准医学的不断发展,生物样本库已从生物样本和信息资源的整合平台,逐步发展为精准医疗研究的支撑服务平台及成果转化的合作平台。此外,生物样本库发展进程中尚存在数据安全、隐私保护及可持续发展运营等问题,亟待规范和完善。In recent years,in the context of"Healthy China",precision medicine and biobanks have ushered in a golden period of rapid development.In the era of precision medicine,as an emerging field in the medical industry,biobanks have their own development trend and characteristics:the development process needs standardization,highly relies on information technology,is inseparable from multi-center alliance and resource sharing,and needs the support of multidisciplinary integration.With the continuous development of precision medicine,biobanks developed from its infancy stage,a platform of biological samples and information resource integration,into a service platform of precision medical study support and a platform of transformation cooperation.In addition,during the development stage of biobanks,there are problems of data security,privacy protection and sustainable operation.

关 键 词：精准医疗 生物样本库 发展特点 建设 

分 类 号：R446.9[医药卫生—诊断学]