药学服务对肾病综合征患儿合理用药的干预效果研究  

Intervention of Pharmaceutical Care on Rational Drug Use in Children with Nephrotic Syndrome

作　　者：段彦彦[1] 马姝丽 裴保方 陈海燕[1] Duan Yanyan;Ma Shuli;Pei Baofang;Chen Haiyan(Children’s Hospital Affiliated to Zhengzhou University,Henan Children’s Hospital,Zhengzhou Children’s Hospital,Henan Zhengzhou 450000,China)

机构地区：[1]郑州大学附属儿童医院,河南省儿童医院,郑州儿童医院,河南郑州450000

出　　处：《儿科药学杂志》2021年第4期40-42,共3页Journal of Pediatric Pharmacy

基　　金：全国医药经济信息网科技创新传播创新工程2017年重点项目,编号CMEI2017KP00210。

摘　　要：目的:评价临床药师开展药学服务对肾病综合征患儿合理用药的影响。方法:抽取我院肾病综合征住院患儿病历非干预组81份(2018年1-6月)及干预组83份(2018年7-12月),比较两组患儿用药依从性、不良反应发生率、治疗效果及对疾病认知方面的差异。结果:干预组和非干预组用药依从性评分为(6.74±1.13)分和(3.25±1.56)分(P<0.05);干预组视物模糊、骨质疏松、糖尿病不良反应发生率分别为3.61%、2.41%、0,均低于非干预组的12.35%、9.87%、4.94%(P<0.05);疾病认知方面干预组优于非干预组(P<0.05)。结论:通过临床药师系统全面的药学服务,能降低肾病综合征患儿药品不良反应的发生率,提高用药的依从性及对疾病的认知程度。Objective:To evaluate the effects of pharmaceutical care by clinical pharmacists on the rational drug use in children with nephrotic syndrome.Methods:Medical records of hospitalized children with nephrotic syndrome in our hospital were collected from 81 cases in the non-intervention group(from Jan.to Jun.2018)and 83 cases in the intervention group(from Jul.to Dec.2018).Differences in medication compliance,incidence of adverse drug reactions,treatment effects and disease cognition between two groups were compared.Results:The medication compliance scores of the intervention group and non-intervention group were respectively(6.74±1.13)points and(3.25±1.56)points(P<0.05).The incidences of adverse drug reactions in the intervention group such as blurred vision,osteoporosis and diabetes were respectively 3.61%,2.41%and 0,lower than 12.35%,9.87%and 4.94%in the non-intervention group(P<0.05).In terms of disease cognition,the intervention group was significantly better than the nonintervention group(P<0.05).Conclusion:Comprehensive pharmaceutical care by clinical pharmacists can reduce the incidence of adverse drug reactions in children with nephrotic syndrome,improve the medication compliance and the degree of cognition of the disease.

关 键 词：临床药师 肾病综合征 用药依从性 药学服务 

分 类 号：R969.3[医药卫生—药理学]