2008-2019年陕西省儿童大骨节病病情监测结果分析  

Analysis of monitoring results of Kashin-Beck disease in children in Shaanxi Province from 2008 to 2019

作　　者：郭鲜妮 徐刚要[1] Guo Xianni;Xu Gangyao(Research Laboratory of Kashin-Beck Disease and Keshan Disease,Shaanxi Institute for Endemic Diseases Control,Xi'an 710003,China)

机构地区：[1]陕西省地方病防治研究所大骨节病克山病防治研究室,西安710003

出　　处：《中华地方病学杂志》2021年第3期195-198,共4页Chinese Journal of Endemiology

基　　金：中央补助地方公共卫生专项资金地方病防治项目(2008-2019)。

摘　　要：目的掌握陕西省大骨节病病情变化,为制定大骨节病防治策略、调整大骨节病防治重点提供科学依据。方法在陕西省,2008年选取4个市6个病区县12个乡(镇)的15个行政村;2009-2011年,按全国大骨节病监测方案抽样要求,每年抽取7个病区县,每个病区县抽取4个乡(镇),每个乡(镇)抽取1个村;2012-2015年,每年选取31个病区县,2016-2018年,分别选取43、12、12个病区县,每个病区县抽取5个乡(镇),每个乡(镇)抽取3个村;2019年抽取全部62个病区县的全部病区村作为调查点。抽取7~12岁儿童(2009-2011年临床检查抽取7~16岁儿童)进行大骨节X线和临床检查。计算大骨节病临床阳性检出率、X线阳性检出率和干骺端阳性检出率,并进行病区病情判定。结果2009-2011年临床共检查7~16岁儿童7628人,2008、2012-2019年临床共检查7~12岁儿童323356人,均未检出大骨节病临床阳性病例。2008-2018年共对114199名7~12岁儿童进行大骨节病X线检查,检出X线阳性48例,检出率为0.04%(48/114199);其中干骺端阳性47例,检出率为0.04%(47/114199)。各年份X线阳性检出率均<3.0%,且2011年后全省儿童大骨节病X线阳性检出率和干骺端阳性检出率一直保持在0.10%以下,处于低位波动。2012-2016、2018、2019年监测的所有病区村均达到了大骨节病消除标准。2017年监测的195个病区村,99.49%(194/195)的病区村达到了消除标准。结论2008-2019年,陕西省大骨节病病情持续下降,病区村大骨节病病情均已达到消除水平,并处于持续消除状态。Objective To master the changes of Kashin-Beck disease(KBD)in Shaanxi Province,and provide scientific basis for formulating the prevention and control strategy of KBD and adjusting the prevention and treatment priorities of KBD.Methods In 2008,15 administrative villages in 12 townships(towns),6 ward counties(districts)of 4 cities of Shaanxi Province were selected as survey points;from 2009 to 2011,according to the sampling requirements of the national Kashin-Beck disease surveillance plan,7 ward counties were selected each year,and 4 townships from each county and 1 village from each township were selected as survey points;from 2012 to 2015,31 ward counties were selected each year,with 5 townships from each county and 3 villages from each township as survey points;from 2016 to 2018,43,12 and 12 ward counties were selected each year,and 5 townships from each county and 3 villages from each township were selected as survey points;in 2019,all ward villages of 62 ward counties were selected as survey points.Children aged 7 to 12 years old(7 to 16 years old in 2009-2011 for clinical examination)were selected for X-ray and clinical examination of KBD.The clinical positive detection rate of KBD,the positive detection rate of X-ray and the positive detection rate of metaphysis were calculated,and the disease condition in KBD areas was determined.Results From 2009 to 2011,a total of 7628 children aged 7 to 16 years old were clinically examined,and a total of 323356 children aged 7 to 12 years old were examined in 2008 and 2012-2019.No clinically positive cases of KBD were detected.From 2008 to 2018,a total of 114199 children aged 7 to 12 years old were examined for KBD.A total of 48 cases were positive on X-ray,with a detection rate of 0.04%(48/114199),of which 47 cases were positive on metaphysis,the detection rate was 0.04%(47/114199).The positive X-ray detection rate in each year was lower than 3.0%,and the positive X-ray detection rate and the positive metaphysis detection rate of KBD in children in the whole province

关 键 词：地方性变形性骨关节炎 监测 临床 X线 干骺端 

分 类 号：R726.8[医药卫生—儿科] R181.8[医药卫生—临床医学]