功能化金纳米材料在肿瘤诊疗中的研究与应用  

Surface Functionalized Gold Nanomaterials in Tumor Diagnosis and Treatment

作　　者：葛浩英 杜健军[1,2] 龙飒然 孙文 樊江莉 彭孝军[1] GE Haoying;DU Jianjun;LONG Saran;SUN Wen;FAN Jiangli;PENG Xiaojun(State Key Laboratory of Fine Chemicals,Dalian University of Technology,Dalian 116024,China;Ningbo Research Institute,Dalian University of Technology,Ningbo 315016,China)

机构地区：[1]大连理工大学精细化工国家重点实验室,大连116024 [2]大连理工大学宁波研究院,宁波315016

出　　处：《高等学校化学学报》2021年第4期1202-1212,共11页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金(批准号:21421005,21676047,21822804,21878039,21925802);NSFC-辽宁联合基金(批准号:U1908202,U1608222)资助.

摘　　要：作为一种重要的贵金属,金具有表面等离子共振的光学特性,在材料、催化和医学诊疗等领域有着广泛且重要的应用.本文综合评述了表面功能化的金纳米材料在肿瘤诊断及治疗领域的相关研究,并对金纳米材料在肿瘤诊疗领域的未来发展进行了展望.As an important noble metal,gold exhibits unique surface plasmon resonance characteristics and has been widely applied in materials,catalysis,medical diagnosis and treatment and so forth.In this review,the surface functionalization of gold nanomaterials and their applications in imagingbased diagnosis and treatment of tumors are reviewed,and the problems that need to be solved in the future for clinical applications are summarized.

关 键 词：金纳米材料 表面等离子共振 临床诊断 光疗 联合治疗 

分 类 号：O614[理学—无机化学]