良、恶性甲状腺结节特征差异的临床分析  

An analysis of the difference between benign and malignant thyroid nodules in clinical characteristics

作　　者：褚晓秋[1] 相萍萍 张会峰[1] 刘超[1] 范尧夫[1] CHU Xiaoqiu;XIANG Pingping;ZHANG Huifeng(Department of Endocrinology,Affiliated Hospital of Integrated Traditional Chinese and Western Medicine,Nanjing University of Chinese Medicine,Nanjing 210028,CHINA)

机构地区：[1]南京中医药大学附属中西医结合医院(江苏省中医药研究院)内分泌科,江苏210028

出　　处：《江苏医药》2021年第2期171-173,共3页Jiangsu Medical Journal

基　　金：江苏省中医院领导人才(SLJ0209)。

摘　　要：目的分析良、恶性甲状腺结节特征的临床差异。方法采用细针穿刺细胞学和甲状腺彩色多普勒超声检查271例甲状腺结节患者(302个结节);其中,248个甲状腺结节有明确病理诊断,分析良、恶性甲状腺结节的临床差异。结果 248个甲状腺结节中,病理诊断良性结节195个,恶性结节53个。良性和恶性甲状腺结节的位置、回声、钙化性质、纵横比和边缘形态差异均有统计学差异(P<0.05)。多因素logistic回归分析显示,位于甲状腺中极和表现为低回声、微钙化、纵横比>1和边缘不光整是恶性甲状腺结节的独立危险因素(P<0.05)。结论位于甲状腺中极、低回声、微钙化、纵横比>1和边缘不光整的甲状腺结节恶性的可能性较大。Objective To analyze the difference between benign and malignant thyroid nodules in clinical characteristics.Methods Fine needle aspiration cytology and thyroid ultrasound examination were performed in 271 patients with 302 thyroid nodules,of which 248 thyroid nodules had definite pathological diagnosis.The differences between benign and malignant thyroid nodules in clinical characteristics were analyzed.Results Of 248 thyroid nodules with pathological diagnosis,195 thyroid nodules were benign and 53 thyroid nodules were malignant.The differences in nodule location,echo,calcified property,aspect ratio and edge morphology were statistically different between benign and malignant thyroid nodules(P<0.05).Multivariate logistic regression analysis showed that the middle pole location,hypoechoic,microcalcification,aspect ratio >1 and uneven edges were the independent risk factors for malignant thyroid nodules(P<0.05).Conclusion The thyroid nodules located at the middle pole and with the manifestations of hypoechoic,microcalcification,aspect ratio >1 and uneven edges are more likely to be malignant.

关 键 词：甲状腺结节 

分 类 号：R581[医药卫生—内分泌]