中西医结合治疗新生儿高胆红素血症临床分析  

Clinical Analysis on the Treatment of Neonatal Hyperbilirubinemia with Integrated Traditional Chinese and Western Medicine

作　　者：陈艳[1] CHEN Yan(Department of Pediatrics,Sheyang County People's Hospital,Yancheng,Jiangsu Province,224300 China)

机构地区：[1]射阳县人民医院儿科,江苏盐城224300

出　　处：《系统医学》2021年第3期101-103,共3页Systems Medicine

摘　　要：目的研究中西医结合治疗新生儿高胆红素血症临床效果。方法将该院2017年1月—2019年12月收治的64例高胆红素血症患儿分为两组,每组32例。对照组接受常规西医治疗,观察组在对照组基础上增加中医治疗方法。比较两组临床指标复常时间、胆红素水平、肝功能指标与临床疗效以及不良反应情况。结果观察组患儿的胆红素下降时间与黄疸消退时间均明显短于对照组,差异有统计学意义(t=11.437、5.279,P<0.05)。治疗后,观察组患儿的胆红素水平明显低于对照组,差异有统计学意义(t=12.120,P<0.05);观察组患儿的ALT、ALP、AST及GGT水平均明显低于对照组,差异有统计学意义(t=4.127、3.070、7.439、4.092,P<0.05)。观察组患儿的治疗总有效率为93.75%,对照组患儿的治疗总有效率为75.00%,差异有统计学意义(χ^(2)=4.267,P=0.0.39)。两组患儿均未出现严重的临床不良反应情况。结论中西医结合治疗新生儿高胆红素血症,其临床效果显著,能快速缓解患儿的临床症状,改善肝脏功能,且临床不良反应较少。Objective To study the clinical effect of combined traditional Chinese and Western medicine in the treatment of neonatal hyperbilirubinemia.Methods The 64 children with hyperbilirubinemia in the hospital from January 2017 to December 2019 were divided into two groups,each with 32 cases.The control group received conventional western medicine treatment,and the observation group added traditional Chinese medicine treatment methods on the basis of the control group.Compared the time to normalization of the two groups of clinical indicators,bilirubin levels,liver function indicators and clinical efficacy and adverse reactions.Results The bilirubin decline time and jaundice resolution time of children in the observation group were significantly shorter than those of the control group.The difference was statistically significant(t=11.437,5.279,P<0.05).After treatment,the bilirubin level of the observation group was significantly lower than that of the control group,.The difference was statistically significant(t=12.120,P<0.05);the observation group had significant levels of ALT,ALP,AST and GGT Lower than the control group.The difference was statistically significant(t=4.127,3.070,7.439,4.092,P<0.05).The total effective rate of treatment for children in the observation group was 93.75%,and that of children in the control group was 75.00%.The difference was statistically significant(χ^(2)=4.267,P=0.039).There were no serious clinical adverse reactions in the two groups of children.Conclusion The treatment of neonatal hyperbilirubinemia with integrated traditional Chinese and western medicine has significant clinical effects,which can quickly relieve the children's clinical symptoms,improve liver function,and have fewer clinical adverse reactions.

关 键 词：中西医 高胆红素血症 不良反应 新生儿 肝功能 

分 类 号：R722.17[医药卫生—儿科]