联用拉贝洛尔和硫酸镁治疗妊娠期高血压综合征的效果及改善其妊娠的结局分析  

Analysis of the Effect of Combined Use of Labetalol and Magnesium Sulfate in the Treatment of Pregnancy-induced Hypertension Syndrome and Improvement of Pregnancy Outcome

作　　者：杨娇娥[1] YANG Jiao-e(The 940 Hospital of the Northwest Joint Logistics Support Force of the Chinese People's Liberation Army,Lanzhou,Gansu Province,730000 China)

机构地区：[1]中国人民解放军西北联勤保障部队第九四〇医院,甘肃兰州730000

出　　处：《世界复合医学》2021年第2期160-162,共3页World Journal of Complex Medicine

摘　　要：目的研究联用拉贝洛尔和硫酸镁治疗妊娠期高血压综合征的效果及对改善妊娠结局的作用。方法通过双盲选法将该院在2019年4月—2020年4月时间段中收治的100例妊娠期高血压综合征患者随机分为参照组(硫酸镁治疗)和研究组(拉贝洛尔、硫酸镁治疗),每组例数均为50例。对其治疗前后的血压水平变化进行比较,同时观察其治疗后的并发症发生情况以及治疗有效率。结果治疗后研究组收缩压(137.48±14.11)mmHg以及舒张压(85.24±4.45)mmHg均显著优于对照组,差异有统计学意义(t=4.616、5.974,P<0.05);治疗后参照组发症发生率(22.00%)显著较研究组(6.00%)高,参照组治疗总有效率(78.00%)显著较研究组(94.00%)低,差异有统计学意义(χ^(2)=5.316、5.316,P<0.05)。结论对于妊娠期高血压综合征患者,选择拉贝洛尔和硫酸镁进行联合治疗有助进一步提高治疗效果,无论是对于患者妊娠结局的改善,还是其血压水平控制效果的提高均具有积极作用。Objective To study the effect of combined use of labetalol and magnesium sulfate in the treatment of pregnancy-induced hypertension syndrome and the improvement of pregnancy outcome.Methods A double-blind selection method was used to randomly divide 100 patients with pregnancy-induced hypertension in the hospital from April 2019 to April 2020 into a reference group(magnesium sulfate treatment)and a study group(labetalol,magnesium sulfate treatment),the number of cases in each group was 50 cases.Compare the changes in blood pressure levels before and after treatment,and observe the occurrence of complications after treatment and the treatment efficiency.Results After treatment,the study group's systolic blood pressure of(137.48±14.11)mmHg and diastolic blood pressure of(85.24±4.45)mmHg were significantly better than those of the control group,and the data difference between the groups was statistically significant(t=4.616,5.974,P<0.05);the reference group after treatment of the incidence rate(22.00%)was significantly higher than that of the study group(6.00%),the total effective rate of treatment in the reference group(78.00%)was significantly lower than that of the study group(94.00%),and the difference in data between the groups was statistically significant(χ^(2)=5.316,5.316,P<0.05).Conclusion For patients with pregnancy-induced hypertension,choosing labetalol and magnesium sulfate for combined therapy can further improve the therapeutic effect.It has a positive effect on both the improvement of the patient’s pregnancy outcome and the improvement of the blood pressure level control effect.

关 键 词：拉贝洛尔 硫酸镁 妊娠期高血压综合征 治疗效果 妊娠结局 

分 类 号：R714.24[医药卫生—妇产科学]