MRI诊断胎儿侧脑室扩张的意义  

Significance of MRI in diagnosis of fetal ventriculomegaly

作　　者：常高瑞 张小安[1] 赵鑫[1] 殷星[1] 栗河舟[2] CHANG Gao-rui;ZHANG Xiao-an;ZHAO Xin;YIN Xing;LI He-zhou(Department of Imaging,The Third Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China;不详)

机构地区：[1]郑州大学第三附属医院影像科,郑州450052 [2]郑州大学第三附属医院超声科,郑州450052

出　　处：《医药论坛杂志》2021年第4期7-11,共5页Journal of Medical Forum

基　　金：河南省医学科技攻关计划(联合共建)项目(LHGJ20190382)。

摘　　要：目的本研究旨在确定胎儿MRI检查在胎儿侧脑室扩张中的应用价值。方法对在郑州大学第三附属医院行超声检查提示胎儿侧脑室扩张并经胎儿MRI检查确诊的病例的羊水穿刺结果、妊娠结局、出生后影像学检查结果及神经发育情况进行回顾性分析。结果合并结构畸形组的死亡率显著高于其他两组,差异有统计学意义(P<0.05)。合并结构畸形组的神经系统发育异常率显著高于单纯组,差异有统计学意义(P<0.05)。三组病例的羊水穿刺检查结果提示,差异无统计学意义(P>0.05)。转归组胎儿出生后的神经系统发育异常率显著低于持续组,差异有统计学意义(P<0.05)。结论当产前超声检查发现胎儿侧脑室扩张时,应在产前行胎儿MRI检查、染色体检查、定期的影像学检查,并在出生后定期行专业的神经发育情况评估以提供更可靠的产前咨询、提高患儿预后。Objective To evaluate the significance of MRI in the diagnosis of fetal ventriculomegaly.Methods The amniocentesis outcomes,the pregnancy outcomes,the postnatal imaging reexamination results and the neurological outcomes of the cases diagnosed as fetal ventriculomegaly by both US and MRI were analyzed retrospectively.Results The mortality of the group with other structural malformations was significantly higher than that of the other two groups(P<0.05).The neurodevelopmental abnormality rate in the group with other structural malformations was significantly higher than that in the simple group(P<0.05).There was no significant difference in amniocentesis results among the three groups(P>0.05).The abnormal rate of neurodevelopment in the resolved VM group was significantly lower than that in the persistent VM group(P<0.05).Conclusion If fetal ventriculomegaly is diagnosied by prenatal ultrasound,fetal MRI,chromosome analysis,regular imaging review should be performed prenatally,and professional neurodevelopmental assessment should be performed regularly postnatally to provide more reliable prenatal consultation and improve the prognosis of children.

关 键 词：胎儿侧脑室扩张 磁共振成像 预后 神经系统发育 

分 类 号：R445[医药卫生—影像医学与核医学]