基于全球疾病负担(GBD)大数据的中国银屑病流行病学负担分析  

Analysis of the Epidemiological Burden of Psoriasis in China Based on the Big Data of Global Burden of Disease Study(GBD)

作　　者：李慧贤 胡丽 郑焱[3] 张键[1] 刘文丽[1] 高田原 牟宽厚[1] 田琼[1] LI Huixian;HU Li;ZHENG Yan;ZHANG Jian;LIU Wenli;GAO Tianyuan;MOU Kuanhou;TIAN Qiong(The First Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710061,China;Department of Pathogen Biology and Immunology,School of Basic Medical Sciences,Xi'an Jiaotong University,Xi'an 710061,China;Department of Dermatology,the Sceond Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710004,China)

机构地区：[1]西安交通大学第一附属医院,陕西西安710061 [2]西安交通大学基础医学院病原生物学与免疫学系,陕西西安710061 [3]西安交通大学第二附属医院皮肤科,陕西西安710004

出　　处：《中国皮肤性病学杂志》2021年第4期386-392,共7页The Chinese Journal of Dermatovenereology

摘　　要：目的分析GBD 2017数据库中国银屑病数据,探讨中国银屑病疾病流行病学负担,为银屑病的防控提供理论依据。方法检索GBD 2017数据库中国银屑病的患病数/率、发病数/率、DALYs/DALY率及中国和全球的社会人口学指数(SDI值),统计中国1990-2017年银屑病的流行趋势及年龄、时期、出生队列趋势,并研究银屑病发病率与SDI之间的关系。结果2017年,中国银屑病患病率及发病率均位于全球偏低水平,患病人数为1990年的1.95倍,患病率、发病率及DALY率均持续上升。中国银屑病发病率年龄趋势呈中间高两头低形态,且男性高于女性。随着SDI值的增加,银屑病的发病率呈线性上升趋势。结论1990-2017年间,中国银屑病疾病负担显著上升,且与社会发展程度呈正相关。积极研究银屑病准确的流行病学资料及与社会发展水平的关系,对于银屑病诊治、卫生政策制定具有重要意义。Objective To analyse the disease epidemiological burden,and provide a theoretical foundation for the prevention and control of psoriasis in China based on the data in GBD 2017.Methods The prevalent cases/prevalence,incident cases/incidence,DALYs of psoriasis and SDI for global and China were searched from the GBD 2017 databas to analyze the epidemiological trend,age-period-cohort trend of psoriasis in China from 1990 to 2017,and evaluate the relations of the incidence of psoriasis and SDI.Results In 2017,the prevalence and incidence of psoriasis in China were both at a low level in the world,however,the number of prevalent cases were 1.95 times of that in 1990.The age-standardised prevalence,incidence and DALY rates continued to rise.The age trend of psoriasis incidence in China was high at the middle of the age stages and low at the two ends,and higher in the male than in the female.With the increase of SDI,the incidence of psoriasis increased linearly.Conclusion The disease burden of psoriasis in China increases significantly and is positively correlated with the social development from 1990 to 2017.It is a great significance to study the relationship between epidemilolgical data of psoriasis and social development level for informing policy regarding psoraisis control strategies.

关 键 词：GBD 2017 中国 银屑病 负担 

分 类 号：R758.63[医药卫生—皮肤病学与性病学]