布地奈德、万托林联合甲强龙治疗小儿毛细支气管炎的临床价值  

The clinical value of budesonide and vantolin combined with methylprednisolone in the treatment of bronchiolitis in children

作　　者：李津玉[1] 武建国[1] LI Jin-yu;WU jian-guo(Department of pediatrics,Xi'an Aerospace general hospital,Xi'an 710100,China)

机构地区：[1]西安航天总医院儿科,陕西西安710100

出　　处：《吉林医学》2021年第4期827-829,共3页Jilin Medical Journal

摘　　要：目的:探讨布地奈德、万托林联合甲强龙治疗小儿毛细支气管炎的临床价值。方法:选取2017年10月~2018年10月儿科收治的毛细支气管炎患儿80例为研究对象,随机分为观察组和对照组,每组40例。两组患儿入院后常规给予吸氧、止咳化痰、抗病毒等治疗,对照组在此基础上将布地奈德混悬液与万托林混合后通过雾化器氧气驱动雾化吸入治疗;观察组在对照组基础上给予静脉滴注甲强龙注射液,观察两组治疗效果及患儿咳嗽、喘憋、肺部喘鸣音及湿啰音持续时间等指标。结果:治疗后观察组治愈率为97.50%,显著高于对照组77.50%,差异有统计学意义(P<0.01);观察组患儿在咳嗽、喘憋、肺部喘鸣音及湿啰音持续时间均短于对照组,差异有统计学意义(P<0.01)。结论:在常规治疗基础上加用布地奈德、万托林联合甲强龙治疗小儿毛细支气管炎有显著疗效,缩短了症状缓解时间,值得临床进一步推广应用。Objective To investigate the clinical value of budenide and vantolin combined with methylprednisolone in the treatment of bronchiolitis in children.Method Eighty children with bronchiolitis admitted to the department of pediatrics of our hospital from October 2017 to October 2018 were selected as the study objects and randomly divided into observation group and control group,40 cases in each group.After admission,the children in the two groups were routinely given oxygen inhalation,antitussive treatment,antiviral treatment,etc.On this basis,the control group was treated with budesonide suspension mixed with vantolin through atomizer oxygen driven atomization inhalation.Observation group on the basis of the control group was given intravenous injection of methylprednisolone injection,to observe the treatment effect of the two groups and the children's cough,wheezing,lung wheezing and the duration of wet rales and other indicators.Results After treatment,the cure rate of the observation group was 97.50%,which was significantly higher than that of the control group(77.50%),and the difference was statistically significant(P<0.01).The duration of cough,wheezing,lung wheezing and moist rumbling in the observation group was shorter than that in the control group(P<0.01).Conclusion On the basis of conventional treatment,budesonide and vantolin combined with methylprednisolone have a significant effect on the treatment of pediatric bronchiolitis,which improves the effective rate of treatment and shortens the time for symptom relief.Therefore,it is worthy of further clinical application.

关 键 词：布地奈德 万托林 甲强龙 小儿毛细支气管炎 

分 类 号：R725.6[医药卫生—儿科]