722实时动态胰岛素泵3C疗法对住院患者的血糖管理疗效研究  

Therapeutic Effect of 722 Real-time Dynamic Insulin Pump 3C Therapy on Blood Glucose Management in Hospitalized Patients

作　　者：江浩[1] JIANG Hao(Xinyi People’s Hospital,Xinyi 525300,China)

机构地区：[1]广东省信宜市人民医院,广东信宜525300

出　　处：《中国医学创新》2021年第2期64-67,共4页Medical Innovation of China

基　　金：茂名市科技计划项目(190403161700825)。

摘　　要：目的:探讨722实时动态胰岛素泵3C疗法对住院患者的血糖管理疗效。方法:选取2018年1月-2019年8月于本院内分泌科住院的120例2型糖尿病患者为研究对象,按随机数字表法将其分为治疗组、对照A与B组,每组40例。治疗组给予722实时动态胰岛素泵3C疗法,对照A组给予三餐前速效胰岛素+长效胰岛素治疗,对照B组给予口服降糖药物治疗。比较三组治疗前后空腹血糖(FPG)、糖化血红蛋白(HbA1c)、胰岛素抵抗指数(HOMA-IR)、平均血糖波动幅度(MAGE),高血糖曲线下面积(AUC),低血糖AUC、低血糖发生率、严重低血糖发生率及住院时间。结果:治疗后,三组HbA1c、MAGE及高血糖AUC均低于治疗前,且治疗组均低于对照A组与B组(P<0.05)。治疗组治疗前后低血糖AUC比较,差异无统计学意义(P>0.05)。治疗后,对照A组与B组低血糖AUC均高于治疗前,且均高于治疗组(P<0.05)。治疗组低血糖及严重低血糖发生率均低于对照A组与B组(P<0.05)。三组平均住院天数比较,差异有统计学意义(P<0.05),其中治疗组最短。结论:722实时动态胰岛素泵3C疗法能有效地控制血糖,减少低血糖的发生风险,缩短患者的住院时间,是有效管理T2DM患者血糖的疗法。Objective:To explore the effect of 722 real-time dynamic insulin pump 3C therapy on blood glucose management in hospitalized patients.Method:A total of 120 patients with type 2 diabetes hospitalized in the department of endocrinology of our hospital from January 2018 to August 2019 were selected as study subjects.According to the random number table method,they were divided into treatment group,control group A and group B,with 40 patients in each group.The treatment group was treated with 722 real-time dynamic insulin pump 3C therapy.The control group A was treated with quick-acting insulin plus long-acting insulin therapy before three meals.The control group B was treated with oral hypoglycemic drugs.Fasting plasma glucose(FPG),glycated hemoglobin(HbA1c),HOMA-IR,mean amplitude of glycemic excuisions(MAGE),area under curve(AUC)of hyperglycemia,AUC of hypoglycemia before and after treatment,incidence of hypoglycemia,incidence of severe hypoglycemia and length of hospital stay were compared among the three groups.Result:After treatment,HbA1c,MAGE and AUC of hyperglycemia among three groups were lower than those before treatment,and those of the treatment group were lower than those of the control group A and group B(P<0.05).There were no significant differences in AUC of hypoglycemia before and after treatment in the treatment group(P>0.05).After treatment,the AUC of hypoglycemia in the control group A and group B were higher than those before treatment,and were higher than those in the treatment group(P<0.05).The incidence of hypoglycemia and severe hypoglycemia in the treatment group were lower than those in the control group A and group B(P<0.05).There was significant difference in the average length of stay among the three groups(P<0.05),among which the treatment group was the shortest.Conclusion:722 real-time dynamic insulin pump 3C therapy can effectively control blood glucose,reduce the risk of hypoglycemia,shorten the hospitalization time of patients,it is an effective treatment to manage blood glucose in p

关 键 词：722实时动态胰岛素泵3C疗法 血糖管理 2型糖尿病 

分 类 号：R587.1[医药卫生—内分泌]