针刺治疗膝骨性关节炎膝关节疼痛的作用机理研究进展及探讨  

Research Progress and Discussion on Pain Mechanisms and Acupuncture Effect Mechanisms of Knee Osteoarthritis

作　　者：李政杰[1] 程施瑞[1] 周俊 贺文华 董晓慧 曾芳[1] 梁繁荣[1] Li Zhengjie;Cheng Shirui;Zhou Jun;He Wenhua;Dong Xiaohui;Zeng Fang;Liang Fanrong(Acupuncture and Tuina School,Chengdu University of TCM,Chengdu 610075,China)

机构地区：[1]成都中医药大学针灸推拿学院,成都610075

出　　处：《世界科学技术-中医药现代化》2021年第1期212-216,共5页Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

基　　金：国家自然科学基金委员会重大项目(81590951):穴位敏化现象和规律的临床研究,负责人:梁繁荣;国家自然科学基金委员会面上项目(81774400):基于“膝为筋之府”理论针刺治疗KOA疼痛认知控制网络整合机制研究,负责人:梁繁荣;全国博士后管委会办公室中国博士后博士后国际交流计划派出项目(20190037):针刺和塞来昔布治疗慢性膝痛临床疗效预测的神经影像学研究,负责人:李政杰。

摘　　要：膝关节疼痛是膝骨性关节炎(Knee Osteoarthritis,KOA)患者求诊的主要原因。针刺治疗膝关节疼痛历史悠久,安全有效,但机理不完全明确。目前研究发现,膝关节局部因素和中枢神经传导通路的改变共同参与了膝关节疼痛的形成。本文从膝关节局部和中枢神经传导通路两方面探讨KOA患者膝关节疼痛和针刺治疗的机理,并对针刺治疗KOA膝关节疼痛的相关研究的开展进行探讨和展望。Knee pain is the main reason for a patient with knee osteoarthritis(KOA) to consult a physician. Acupuncture treatment for knee pain is safe and effective and it has a long history. However, the mechanism is not fully clarified. At present, it has been found that local factors of the knee joint and changes of nerve conduction pathway were related to knee pain. This paper discussed mechanisms of knee pain in patients with KOA and acupuncture effect from perspectives of local knee joint factor and nerve conduction pathway factor. At the same time, the research on acupuncture for treating knee pain was discussed and predictions were made.

关 键 词：针刺 膝骨性关节炎 膝痛 中枢机制 外周机制 

分 类 号：R245[医药卫生—针灸推拿学]