痴呆患者精神行为症状治疗的研究进展  

Research progress in the treatment of behavioral and psychological symptoms in dementia patients

作　　者：董萌 罗海彦[1] DONG Meng;LUO Hai-yan(Department of Neurology,the Second Affiliated Hospital of Chongqing Medical University,Chongqing400010,China)

机构地区：[1]重庆医科大学附属第二医院神经内科,重庆400010

出　　处：《中国当代医药》2021年第10期44-47,53,共5页China Modern Medicine

摘　　要：约90%以上的痴呆患者都伴有精神行为症状,其临床类型多变,且涉及的发病机制尚不明确,因此对痴呆患者的精神行为症状治疗和管理仍较为棘手。近年来,痴呆精神行为症状发病机制上有了一些新的理论进展,使得非药物干预在治疗中的地位进一步提高,不少国内外指南都将非药物干预作为一线推荐,药物治疗作为重要的补充手段。对痴呆患者的精神行为治疗最好采用个体化的方案,本文将对非药物干预和药物治疗的研究进展进行阐述,重点在于如何细化非药物干预治疗和根据患者情况选择相应的药物治疗。Almost more than 90%people with dementia suffer from behavioral and psychological symptoms,whose clinical types are varied,and the pathogenesis involved is not clear.Therefore,the treatment and management of neuropsychiatric signs and symptoms in dementia patients are still difficult.In recent years,there have been some new theoretical progress in the behavioral and psychological symptoms of dementia,which has further enhanced the status of non-pharmacologic intervention in treatment.Many domestic and foreign guidelines have recommended non-pharmacologic intervention as the first line,and pharmacologic therapy as an important complementary means.It′s better to make individual treatment program for dementia patients with behavioral and psychological symptoms.This paper will elaborate the research progress of non-pharmacologic intervention and pharmacologic therapy,focusing on how to refine the non-pharmacologic intervention therapy and select the corresponding pharmacologic therapy according to the patients′situation.

关 键 词：痴呆 精神行为症状 非药物干预 药物治疗 

分 类 号：R651.15[医药卫生—外科学]