低频下降型突发性耳聋临床因素与预后相关性研究  

A Study on Clinical Factors and Prognostic Correlations forLow-frequency Descending Sudden Deafness

作　　者：郭子雯 姚慧敏 王华[1] 范佳 赵花香 陈琼[1] 董朝安 江文[1] GUO Zi-wen;YAO Hui-min;WANG Hua;FAN Jia;ZHAO Hua-xiang;CHEN Qiong;DONG Chao-an;JIANG Wen(Department of Otolaryngology, 921 Hospital of the People's Liberation Army of China, Second Affiliated Hospital, Hunan Normal University, Changsha 410003, China)

机构地区：[1]湖南师范大学附属第二医院,中国人民解放军联勤保障部队第九二一医院耳鼻喉科,中国长沙410003

出　　处：《湖南师范大学自然科学学报》2021年第2期54-59,共6页Journal of Natural Science of Hunan Normal University

基　　金：军委后勤保障部保健课题(20BJZ22);湖南省残联课题(2020XK035);湖南省教育厅课题(20A307,20C1169)。

摘　　要：目的观察低频下降型突发性耳聋的临床疗效,探索相关因素对预后的影响。方法回顾性分析60例单侧低频听力下降型突发性耳聋患者,按照性别、年龄、患耳侧别、身体质量指数(BMI)值、发病至就诊时间、入院时纯音听阈(PTA)、畸变产物耳声发射(DPOAE)检查的DP值及SNR等分组。根据治疗结果分为有效、无效两组,比较各因素与疗效间的相关性。结果在本研究中,低频下降型突发性耳聋发病年龄、BMI值、入院时250 Hz,500 Hz和1 kHz处PTA与预后疗效差异有统计学意义(P<0.05),而发病至就诊时间、入院时1 kHz处DPOAE DP值及SNR与预后疗效有显著意义(P<0.01)。结论在低频下降型突发性耳聋中,年龄在55岁及以上的老年群体、BMI值在24及以上的偏胖人群、发病至就诊时间在7 d及以上的患者,预后疗效较差。入院后可依据1 kHz处DPOAE DP值及SNR预估患者疗效,提高患者治疗信心。同时提示老年群体及高体质量人群尽早关注自身听力健康。Objective To investigate the clinical efficacy of low-frequency descending sudden deafness and explore the influence of related factors on prognosis.Methods This is a retrospective analysis of 60 patients with unilateral low-frequency type sudden deafness,grouped according to gender,age,side of the affected ear,body mass index(BMI)value,time from onset to consultation,pure tone hearing threshold(PTA)at admission,DP value of distortion product otoacoustic emission(DPOAE)examination and SNR.The groups were divided into effective and ineffective groups according to the treatment outcome,and the correlation between each factor and the efficacy was compared.Results In this study,the factors of the age at onset,BMI,PTA at 250 Hz,500 Hz and 1 kHz at admission were statistically significant(P<0.05),while the factors of time from onset to consultation,DP value,and SNR of DPOAE at 1 kHz at admission were statistically significant(P<0.01)in relation to the prognostic outcome in low-frequency hearing loss sudden deafness.Conclusion In low-frequency descending sudden deafness,the prognostic outcome is poorer in older age groups aged 55 years and older,in obese people groups with BMI values of 24 and larger,and in patients with onset-to-visit days of 7 days and longer.The DPOAE DP value at 1 kHz and SNR can be used to predict the outcome of patients after admission to improve their confidence in treatment.It also suggests that the elderly and over-weight groups should pay more attention to their hearing health as early as possible.

关 键 词：低频下降 身体质量指数 畸变产物耳声发射 疗效 

分 类 号：R764.4[医药卫生—耳鼻咽喉科]