以叙事护理为指导的全程心理护理在CIK生物免疫疗法治疗恶性肿瘤中的应用及对患者生存质量的影响  

The application of whole-course psychological nursing guided by narrative care in the treatment of malignant tumors by CIK bio-immunotherapy and its effect on patients'quality of life

作　　者：张玉峰 Zhang Yufeng(Department of Gastrointestinal Surgery,Luoyang Central Hospital Affiliated to Zhengzhou University,Luoyang City of Henan Province 471000,China)

机构地区：[1]郑州大学附属洛阳中心医院胃肠外科,471000

出　　处：《国际护理学杂志》2021年第7期1188-1193,共6页international journal of nursing

基　　金：河南省科技攻关项目(1921023100395)。

摘　　要：目的探讨以"叙事护理"为指导的全程心理护理在CIK生物免疫疗法治疗恶性肿瘤中的应用及对患者生存质量的影响。方法选取该院收治的恶性肿瘤患者120例为研究对象,分为实验组60例和对照组60例,所有患者均给予CIK生物免疫疗法治疗,实验组在进行常规护理干预的同时给予"叙事护理"为指导的全程心理护理干预,对照组给予常规护理干预,对两组患者近期疗效、不良反应发生情况、对护理工作的满意度及治疗后1个月患者的生存质量进行对比分析。结果所有患者均顺利完成CIK治疗,实验组总有效率高于对照组,但差异无统计学意义(P>0.05)。在治疗期间两组患者均有个别出现发热、皮肤瘙痒及皮疹、乏力困倦、关节肌肉酸痛等1种或几种不良反应,但症状均较轻微,经对症处理后或自行缓解,未出现血常规、肝肾功能检测异常病例,两组患者不良反应发生率差异无统计学意义(P>0.05)。实验组患者或家属对护理工作的满意度调查问卷评分和满意率明显高于对照组,护理投诉率明显低于对照组(P<0.05或P<0.01)。两组患者治疗后1个月KPS评分以及EORTC QLQ-C30量表各领域评分均较治疗前明显改善,且实验组改善更为明显,差异有统计学意义(P<0.05)。结论以"叙事护理"为指导的全程心理护理增强了恶性肿瘤患者对CIK生物免疫疗法的信心,有助于患者积极地配合治疗及护理工作,对改善患者对护理工作的满意度及生存质量具有重要作用。Objective To investigate the application of whole-course psychological nursing guided by"narrative care"in the treatment of malignant tumors by CIK bio-immunotherapy and its effect on patients'quality of life.Methods A total of 120 patients with malignant tumor were selected and divided into experimental group(60 cases)and control group(60 cases).All the patients were treated with CIK bio-immunotherapy,the experimental group was given whole-process psychological nursing guided by"narrative care"while routine nursing intervention,and the control group was given routine nursing intervention.The short-term efficacy,the occurrence of adverse reactions,the satisfaction with the nursing work and the life quality of the patients 1 month after treatment were compared and analyzed.Results All patients successfully completed CIK treatment.The total effective rate of the experimental group was higher than that of the control group,but the difference had no statistical significance(P>0.05).During the treatment,1 or several adverse reactions,including fever,pruritus and rash,fatigue and drowsiness,and joint and muscle soreness,were found in both groups,but the symptoms were mild,which were all relieved after symptomatic treatment or spontaneous remission,without abnormal cases of blood routine and liver and kidney function detection,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).The satisfaction rating and satisfaction rate of patients or family members in the experimental group were significantly higher than those of the control group,and the complaint rate of nursing was significantly lower than that of the control group(P<0.05 or P<0.01).The Karnofsky Performance Status(KPS)score and European Organization for Reasearch and Treatment of Cancer Quality of Life Questionnare-Core 30(EORTC QLQ-C30)scale of the two groups were significantly improved in all areas 1 month after treatment compared with that before treatment,and the improvement was more obvious in the experim

关 键 词：细胞因子诱导的杀伤细胞 生物免疫疗法 肿瘤 护理 生存质量 

分 类 号：R473.73[医药卫生—护理学]