健脾涤痰方治疗稳定期支气管扩张症脾虚痰盛证临床观察  

Clinical Observation of Spleen-Fortifying Phlegm-Removing Decoction in Treating Stable Bronchiectasis with Spleen Deficiency and Phlegm Excess Syndrome

作　　者：罗伟贤[1] 陈建飞[1] 孙广信 李坤 杨泽锋[1] 任连军[1] LUO Wei-xian;CHEN Jian-fei;SUN Guang-xin;LI Kun;YANG Ze-feng;REN Lian-jun(Zhengzhou First People's Hospital,Zhengzhou,Henan,China,450004;Zhengzhou People's Hospital,Zhengzhou,Henan,China,450003)

机构地区：[1]郑州市第一人民医院,河南郑州450004 [2]郑州人民医院,河南郑州450003

出　　处：《河南中医》2021年第4期593-596,共4页Henan Traditional Chinese Medicine

基　　金：河南省医学科技攻关计划项目(2018)(2018020726)。

摘　　要：目的:观察健脾涤痰方治疗稳定期支气管扩张症脾虚痰盛证的临床疗效。方法:将48例支气管扩张症脾虚痰盛证患者,按照随机数字表法分为对照组和治疗组,每组24例。48例患者中脱落3例,治疗组脱落2例,对照组脱落1例。急性加重时,两组患者均给予化痰药、抗菌药物对症治疗,治疗组另给予健脾涤痰方治疗,对照组另给予安慰剂口服。观察两组治疗前后中医证候积分、24 h痰量积分、肺功能、圣乔治呼吸问卷(St George's respiratory questionnaire,SGRQ)积分等变化情况。结果:对照组观察期间7例患者出现急性加重情况,治疗组观察期间未出现急性加重情况。对照组有效率为0,治疗组有效率为90.91%,两组有效率比较,差异有统计学意义(P<0.05)。治疗组治疗后中医证候积分低于治疗前及对照组治疗后,差异有统计学意义(P<0.05);治疗组治疗后24 h痰量少于治疗前及对照组治疗后,差异有统计学意义(P<0.05);治疗组治疗后SGRQ评分低于治疗前及对照组治疗后,差异有统计学意义(P<0.05);治疗组治疗后肺功能优于治疗前及对照组治疗后,差异有统计学意义(P<0.05)。结论:健脾涤痰方能改善稳定期支气管扩张症脾虚痰盛证患者临床症状,提高患者生活质量,减少痰量,改善肺功能。Objective:To observe the clinical curative effect of Spleen-Fortifying Phlegm-Removing Decoction on stable bronchiectasis with spleen deficiency and phlegm excess syndrome.Methods:A total of 48 patients of bronchiectasis with spleen deficiency and phlegm excess syndrome were randomly divided into the control group and the treatment group,with 24 cases in each group.Among the 48 patients,3 cases fell off altogether,2 cases fell off in the treatment group and 1 case fell off in the control group.In case of acute exacerbation,both groups were given expectorant and antibacterial drugs,while the treatment group was additionally given Spleen-Fortifying Phlegm-Removing Decoction,and the control group was additionally given placebo.The changes of TCM syndrome scores,24-hour sputum volume score,lung function and St George's Respiratory Questionnaire(SGRQ)score were observed before and after the treatment.Results:During the observation period,7 patients in the control group had acute exacerbation,while the treatment group had no acute exacerbation.The effective rate of the control group was 0,while that of the treatment group was 90.91%,and the difference was statistically significant(P<0.05).After treatment,the TCM syndrome scores of the treatment group were lower than those of the control group before treatment and after treatment,and all the differences were statistically significant(P<0.05);the sputum volume of the treatment group after 24 hours was less than that before treatment and after treatment of the control group,and all the differences werestatistically significant(P<0.05);The SGRQ score of the treatment group was lower than that before treatment and after treatment of the control group,and all the differences were statistically significant(P<0.05);the pulmonary function of the treatment group was better than that before treatment and after treatment of the control group,and all the differences were statistically significant(P<0.05).Conclusion:Spleen-Fortifying Phlegm-Removing Decoction can improve the clinica

关 键 词：支气管扩张症 稳定期 脾虚痰盛证 健脾涤痰方 

分 类 号：R259.6222[医药卫生—中西医结合]