超声造影联合定量分析在甲状腺结节良恶性鉴别中的应用分析  

Application of CEUS with Quantitative Analysis in the Differential Diagnosis between Malignant and Benign Thyroid Nodules

作　　者：杨坤[1] 许宇光[1] 黄巍 YANG Kun;XU Yuguang;HUANG Wei(The People’s Hospital of Zhongshan,Zhongshan 528400,China;不详)

机构地区：[1]广东省中山市人民医院,广东中山528400

出　　处：《中国医学创新》2021年第4期40-44,共5页Medical Innovation of China

基　　金：中山市医学科研项目(2019A020080)。

摘　　要：目的:探讨超声造影联合定量分析在鉴别甲状腺结节良恶性中的价值。方法:回顾性分析2017年10月-2019年10月在本院行超声造影检查的105例患者资料。以手术病理检查结果为金标准进行对照,并取周围正常组织,分析甲状腺结节超声造影(contrast-enhanced ultrasound,CEUS)的检查结果,并比较不同类型病理组织TIC曲线的定量参数。结果:CEUS检查对甲状腺恶性结节的诊断灵敏度为97.62%,特异度为88.42%,准确度为91.24%。CEUS显示的甲状腺腺瘤和结节性甲状腺肿呈均匀整体高增强或等增强,甲状腺乳头状癌呈不均匀低增强。乳头状癌TIC曲线PI与AUC较周围正常组织均低,差异均有统计学意义(P<0.05)。结论:CEUS联合定量分析对提高甲状腺良恶性结节的确诊率具有积极意义,值得临床推广应用。Objective:To discuss the value of CEUS with quantitative analysis in differential diagnosis between malignant and benign thyroid nodules.Method:Retrospectively analyzed the data of 105 patients who underwent contrast-enhanced ultrasound(CEUS)examination in our hospital from October 2017 to October 2019.The results of surgical pathology were used as the gold standard for comparison,taken normal tissue,the CEUS examination results of thyroid nodules were analyzed,the quantitative parameters of TIC curves of different types of pathological tissues were compared.Result:The diagnosis of malignant thyroid nodules’sensitivity,specificity and accuracy of CEUS were 97.62%,88.42%and 91.24%.CEUS showed that of thyroid adenomas and nodular goitre showed uniform overall high or equal enhancement,thyroid papillary carcinoma showed uneven low enhancement.TIC curve PI and AUC of papillary carcinoma were lower than those of surrounding normal tissues,the difference were statistically significant(P<0.05).Conclusion:CEUS combined quantitative analysis has positive significance in improving the differential diagnosis between malignant and benign,it is worthy of clinical application.

关 键 词：超声造影 定量分析 甲状腺结节 良恶性鉴别 

分 类 号：R445.1[医药卫生—影像医学与核医学] R736.1[医药卫生—诊断学]