探析在冠心病患者临床检验中血清胆红素与尿酸的应用价值  

Probe into the Application Value of Serum Bilirubin and Uric Acid in Clinical Examination of Patients with Coronary Heart Disease

作　　者：马坤[1] 刘萍[2] MA Kun;LIU Ping(Department of Laboratory Medicine,Laiwu Central Hospital,Xinwen Mining Group,Laiwu,Shandong Province,271103 China;Department of Cardiology,Laiwu Central Hospital,Xinwen Mining Group,Laiwu,Shandong Province,271103 China)

机构地区：[1]新汶矿业集团莱芜中心医院检验科,山东莱芜271103 [2]新汶矿业集团莱芜中心医院心内科,山东莱芜271103

出　　处：《中外医疗》2021年第6期14-16,共3页China & Foreign Medical Treatment

摘　　要：目的分析冠心病(简称CHD)患者在临床检验中使用血清胆红素和尿酸(简称UA)的价值。方法A组研究主体为方便选取2017年2月—2020年2月间来该院治疗的86例CHD患者。B组研究主体为同期入院体检的85名健康人员。均对其进行血清胆红素、UA检验,方法为:空腹12 h后采集5 mL静脉血,离心处理血液15 min,分离血清与血浆后,将血清置于生化管内,用生化分析仪检测血清中的血清胆红素、UA值,对比检验结果。结果A组的总胆红素值(T-BIL)(11.25±2.06)μmol/L低于B组(16.41±2.13)μmol/L,差异有统计学意义(t=16.103,P<0.001);A组的间接胆红素值(I-BIL)(6.51±0.57)μmol/L低于B组(9.72±0.69)μmol/L,差异有统计学意义(t=33.182,P<0.001);A组的直接胆红素值(D-BIL)(4.45±0.91)μmol/L低于B组(6.89±1.08)μmol/L(t=15.983,P<0.001);A组的UA值(365.14±20.15)μmol/L高于B组(274.65±18.65)μmol/L,差异有统计学意义(t=30.467,P<0.001)。A组不同病情程度的两项指标对比差异有统计学意义(P<0.05)。结论为CHD患者行血清胆红素与UA检验可有效检出疾病,应作为敏感性诊断指标,并能评估预后,指导临床治疗方案的合理化选择,最大程度上保证疗效。Objective To analyze the value of serum bilirubin and uric acid(UA)in patients with coronary heart disease(CHD)in clinical testing.Methods Convenient select the subjects of group A were 86 CHD patients who came to the hospital for treatment from February 2017 to February 2020.The subjects of group B were 85 healthy persons who were admitted to the hospital for physical examination during the same period.All were tested for serum bilirubin and UA by collecting 5 mL of venous blood after 12 hours of fasting,centrifuging the blood for 15 minutes,separating the serum and plasma,placing the serum in a biochemical tube,and detecting the serum with a biochemical analyzer Contrast the test results with the serum bilirubin and UA values in.Results The total bilirubin value(T-BIL)(11.25±2.06)μmol/L of group A was lower than that of group B(16.41±2.13)μmol/L,the difference was statistically significant(t=16.103,P<0.001);the indirect bilirubin of group A The value(I-BIL)(6.51±0.57)μmol/L was lower than that of group B(9.72±0.69)μmol/L,the difference was statistically significant(t=33.182,P<0.001);the direct bilirubin value(D-BIL)of group A(4.45±0.91)μmol/L was lower than group B(6.89±1.08)μmol/L,the difference was statistically significant(t=15.983,P<0.001);the UA value of group A(365.14±20.15)μmol/L was higher than group B(274.65±18.65)mmol/L,the difference was statistically significant(t=30.467,P<0.001).There was statistically significant difference in the two indicators of different disease severity in group A(P<0.05).Conclusion Serum bilirubin and UA tests for CHD patients can effectively detect the disease,and should be used as sensitive diagnostic indicators,and can evaluate the prognosis,guide the rational choice of clinical treatment options,and ensure the efficacy to the greatest extent.

关 键 词：冠心病 临床检验 血清胆红素 尿酸 

分 类 号：R4[医药卫生—临床医学]