对氯甲苯选择性氧化制备对氯苯甲醛  

Selective Oxidation of p-Chlorotoluene to p-Chlorobenzaldehyde

作　　者：魏世明 胡家明 薛艺 张锋[1] WEI Shiming;HU Jiaming;XUE Yi;ZHANG Feng(School of Chemistry and Chemical Engineering,Nanjing University,Nanjing 210023,China)

机构地区：[1]南京大学化学化工学院,江苏南京210023

出　　处：《化学反应工程与工艺》2020年第1期60-67,共8页Chemical Reaction Engineering and Technology

基　　金：国家自然科学基金项目(21776122)。

摘　　要：为实现绿色、高效生产对氯苯甲醛,采用氧气氧化对氯甲苯选择性制备对氯苯甲醛,选择以MC(Mid-Century)催化剂为基础催化剂,醋酸作溶剂,筛选助催化剂,探究对氯甲苯转化率和对氯苯甲醛收率的影响因素,并设计正交实验获取优化反应条件。结果表明反应温度为80℃,催化剂用量为对氯甲苯质量的4%,钴盐和锰盐质量比为3:1,对氯甲苯和醋酸体积比为1:2,助催化剂用量为对氯甲苯质量的0.625%时,对氯甲苯转化率可达31.42%,对氯苯甲醛的选择性达81.14%。在此基础上,通过反应动力学计算,得到了各温度下的反应速率常数和反应活化能。In order to achieve green and efficient production of p-chlorobenzaldehyde(PCAD),PCAD was selectively prepared by oxidation of p-chlorotoluene(PCT)with O2.MC(Mid-century)catalyst was used as the base catalyst and acetic acid was selected as the solvent.The effects of co-catalyst and other factors on PCT conversion and PCAD selectivity were investigated.Then orthogonal experiments were designed to obtain optimized reaction conditions.The results showed that when the reaction temperature was 80℃,the amount of catalyst used was 4%by mass of PCT,the mass ratio of cobalt salt and manganese salt was 3:1,the volume ratio of PCT and acetic acid was 1:2,and the amount of co-catalyst was 0.625%by mass of PCT,the conversion of PCT could reach 31.42%,and the selectivity of PCAD can reach 81.14%.On this basis,the reaction kinetics was studied,the reaction rate constant and reaction activation energy were obtained.

关 键 词：对氯甲苯 对氯苯甲醛 液相氧化动力学 

分 类 号：O643.32[理学—物理化学]