新型冠状病毒灭活疫苗接种后的针后贴和受种者手部标本核酸检测情况的研究  

Research study on nucleic acid testing of hemostatic stickers used and the surface of the recipients′hands after the inoculation of inactivated SARS-CoV-2 vaccine

作　　者：樊高威 梁玉芳[2] 马雪[3] 刘冰[4] 王京[5] 路璐[3] 李桂芹[4] 金雯 顾佳[5] 王明刚[6] 王清涛 Fan Gaowei;Liang Yufang;Ma Xue;Liu Bing;Wang Jing;Lu Lu;Li Guiqin;Jin Wen;Gu Jia;Wang Minggang;Wang Qingtao(Beijing Centers for Clinical Laboratories,Beijing 100020,China;Department of Clinical Laboratory,Beijing Chao-Yang Hospital,Capital Medical University,Beijing 100020,China;Department of Medical Affairs,Beijing Chao-Yang Hospital,Capital Medical University,Beijing 100020,China;Department of Hospital Management and Disease Control,Beijing Chao-Yang Hospital,Capital Medical University,Beijing 100020,China;Department of Research,Beijing Chao-Yang Hospital,Capital Medical University,Beijing 100020,China;Outpatient Office,Beijing Chao-Yang Hospital,Capital Medical University,Beijing 100020,China)

机构地区：[1]北京市临床检验中心,北京100020 [2]首都医科大学附属北京朝阳医院检验科,北京100020 [3]首都医科大学附属北京朝阳医院医务处,北京100020 [4]首都医科大学附属北京朝阳医院感染管理与疾病预防控制处,北京100020 [5]首都医科大学附属北京朝阳医院科研处,北京100020 [6]首都医科大学附属北京朝阳医院门诊办公室,北京100020

出　　处：《中华预防医学杂志》2021年第3期406-408,共3页Chinese Journal of Preventive Medicine

基　　金：北京市医院管理局临床医学发展专项经费资助项目(ZYLX201811);国家自然科学基金(81702077);北京市医院管理中心“青苗”计划专项经费资助(QML20200310);北京市临床重点专科卓越项目(2020)。

摘　　要：从2021年1月30日接种新型冠状病毒灭活疫苗的首都医科大学附属北京朝阳医院工作人员中选择28位受试者作为研究对象进行研究,在疫苗接种前后分别对受种者的双手进行采样核酸检测的同时,对接种疫苗后粘贴在接种部位的针后贴进行核酸检测。接种疫苗前,受种者双手表面采集的标本核酸检测结果均为阴性。接种疫苗后,受种者双手表面采集的标本核酸检测结果阳性共3例,核酸检测结果可疑共8例,阳性率占10.7%;共收集25例使用过的针后贴标本,核酸检测结果阳性24例,核酸检测结果可疑1例,阳性率占96%。新型冠状病毒灭活疫苗接种的针后贴存在核酸污染的风险。Among the staff of Beijing Chao-Yang Hospital,Capital Medical University,who received the inactivated SARS-CoV-2 vaccine on January 30 in 2021,28 recipients were selected for this research.Samples for nucleic acid tests were collected from the surface of the recipients′both hands before and after vaccination.The hemostatic stickers used after the inoculation were also collected for nucleic acid tests.The nucleic acid tests of the samples collected from the surface of both hands of the 28 recipients before vaccination were all negative.After vaccination,the nucleic acid tests of the samples collected from the surface of both hands of recipients were positive in 3 cases,and suspicious in 8 cases,with a positive rate of 10.7%.A total of 25 hemostatic stickers used were collected,24 of them had positive nucleic acid tests,and the rest one had suspicious nucleic acid test result,with a positive rate of 96%.The hemostatic stickers used after the inoculation have the risk of nucleic acid contamination.

关 键 词：新型冠状病毒 灭活疫苗 核酸检测 受种者 

分 类 号：R186[医药卫生—流行病学]