乙二胺四乙酸二酐的合成影响因素探究及HPLC检测方法的建立  

Synthesis and Characterization of Ethylenediaminetetraacetic Dianhydride

作　　者：武强 王源升[1] WU Qiang;WANG Yuan-sheng(Naval University of Engineering Department of Basic Courses,Wuhan 430033,China)

机构地区：[1]海军工程大学基础部,武汉430033

出　　处：《当代化工》2021年第2期281-286,共6页Contemporary Chemical Industry

基　　金：国防预研项目,舰船螺旋桨及影响区原位智能修复材料与方法机理研究(项目编号:6140004040101)。

摘　　要：采用EDTA和乙酸酐反应合成乙二胺四乙酸二酐(EDTAD)的制备方法,使用三乙胺作为新型化学催化剂和反应溶剂,探究了EDTAD的关键合成影响因素,最终确认该合成方法工艺简单、安全低毒且化学反应收率高;同时建立了快速准确定量EDTAD纯度的高效液相色谱(HPLC)检测方法,为进一步指导制备与加工、成型各类吸附材料,根据需求调控材料结构与性能提供了研究基础。Using the preparation method of ethylenediaminetetraacetic dianhydride(EDTAD) through EDTA ethylenediamine tetraacetic acid and acetic anhydride reaction, with triethylamine as a new type of chemical solvent and catalyst, the key influence factors of EDTAD synthesis were explored, it was finally confirmed that the synthesis process was simple, safe and low toxic and had high chemical reaction yield. A fast and accurate HPLC method for determination of EDTAD purity was established. The research foundation can provide the basis for adjusting the structure and properties of materials according to the demand.

关 键 词：乙二胺四乙酸二酐 苯甲醇 合成 HPLC方法 

分 类 号：O622.5[理学—有机化学]