硫酸镁联合拉贝洛尔治疗妊高征的临床效果及对子宫动脉血流参数的影响  

Clinical effect of magnesium sulfate combined with labetalol in the treatment of pregnancy induced hypertension and its influence on uterine artery blood flow parameters

作　　者：王佳 WANG Jia(Obstetrics and Gynecology Department,Nanyuan Hospital of Fengtai District,Beijing 100076,China)

机构地区：[1]北京丰台区南苑医院妇产科,北京100076

出　　处：《临床医学研究与实践》2021年第11期145-147,共3页Clinical Research and Practice

摘　　要：目的探讨硫酸镁联合拉贝洛尔治疗妊高征的临床效果及对子宫动脉血流参数的影响。方法将我院收治的120妊高征患者按随机数字表法分为观察组(60例,硫酸镁+拉贝洛尔)和对照组(60例,硫酸镁)。比较两组治疗前、后的妊高征相关指标、子宫动脉血流参数、胎儿心功能指标及不良妊娠结局发生情况。结果治疗后,观察组的SBP、DBP、24 h尿蛋白、AFP水平、RI、PI、S/D及胎儿左、右心室Tei指数均低于对照组(P<0.05)。观察组的不良妊娠结局总发生率低于对照组(P<0.05)。结论硫酸镁联合拉贝洛尔治疗妊高征可有效降低血压,改善子宫内动脉血流情况,提高胎儿心功能,优化妊娠结局。Objective To investigate the clinical effect of magnesium sulfate combined with labetalol in the treatment of pregnancy induced hypertension and its influence on uterine artery blood flow parameters.Methods A total of 120 patients with pregnancy induced hypertension admitted in our hospital were divided into observation group(60 cases,magnesium sulfate+labetalol)and control group(60 cases,magnesium sulfate)according to random number table method.The related indexes of pregnancy induced hypertension,uterine artery blood flow parameters,fetal heart function before and after treatment and adverse pregnancy outcomes were compared between the two groups.Results After treatment,SBP,DBP,24 h urinary protein,AFP levels,RI,PI,S/D and Tei index of fetal left and right ventricle in the observation group were lower than those in the control group(P<0.05).The total incidence of adverse pregnancy outcomes in the observation group was lower than that in the control group(P<0.05).Conclusion Magnesium sulfate combined with labetalol in the treatment of pregnancy induced hypertension can effectively reduce blood pressure,improve intrauterine artery blood flow,and fetal heart function,and optimize pregnancy outcome.

关 键 词：拉贝洛尔 妊高征 子宫动脉血流 胎儿心功能 

分 类 号：R714.246[医药卫生—妇产科学]