平均血小板体积与急性冠状动脉综合征的研究进展  

Research progress of mean platelet volume and acute coronary syndrome

作　　者：田增玉 陈小丽 任艳琴[2] 李建国[2] TIAN Zeng-yu;CHEN Xiao-li;REN Yan-qin;LI Jian-guo(Fenyang College,Shanxi Medical University,Tianyuan 030000,China;Department of Cardiology,Fenyang Hospital Affiliated to Shanxi Medical University,Fengyang 032200,China)

机构地区：[1]山西医科大学汾阳学院,山西省太原市030000 [2]山西医科大学附属汾阳医院心内科

出　　处：《中国心血管病研究》2021年第3期279-283,共5页Chinese Journal of Cardiovascular Research

基　　金：山西省重点研发计划项目(201603D321062)。

摘　　要：血小板在止血和血栓形成中发挥显著作用,活化的血小板通过释放参与炎症、动脉粥样硬化和血栓形成的介质,在心血管疾病的发病机制中发挥重要作用。平均血小板体积是血小板大小和活性的指标。大血小板的代谢和酶促活性更强,具有更强的促炎和血栓形成潜力,与急性冠状动脉综合征的发生发展密切相关。Platelets are actively involved in hemostasis and thrombosis.Activated platelets play an important role in the pathogenesis of cardiovascular disease by releasing many mediators involved in inflammation,atherosclerosis and thrombosis.Mean platelet volume is accepted as an indicator of platelet size and platelet activation.Large platelets are metabolically and enzymatically more active,which have a higher tendency to enhance inflammatory processes and thrombotic risk and are closely related to the occurrence and development of acute coronary syndrome.

关 键 词：急性冠状动脉综合征 平均血小板体积 生物标志物 

分 类 号：R543.3[医药卫生—心血管疾病]