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作 者:沈晓敏 姚芳园 沈贤新 黄婷 徐璟 郑芸 SHEN Xiaomin;YAO Fangyuan;SHEN Xianxin;HUANG Ting;XU Jing;ZHENG Yun
机构地区:[1]杭州市妇产科医院儿童保健科,浙江杭州310000
出 处:《新中医》2021年第5期175-178,共4页New Chinese Medicine
摘 要:目的:研究儿童生长贴联合艾灸、运动操及饮食习惯调整相结合的方式对儿童身高改善的影响。方法:纳入身高偏矮患儿58例为研究对象,随机分为研究组(儿童生长贴联合艾灸、运动操与饮食习惯调整)与对照组(饮食指导)各29例,比较血清指标、身高增值与生长速度、有效率与不良反应。结果:2组干预3个月的身高增值与生长速度比较,差异无统计学意义(P>0.05);干预6个月后与对照组比较,研究组身高增值与生长速度高(P<0.05)。2组干预前胰岛素样生长因子-1 (IGF-1)与胰岛素样生长因子结合蛋白-3 (IGFBP-3)水平比较,差异无统计学意义(P>0.05);干预后与对照组比较,研究组IGF-1与IGFBP-3水平均更高(P<0.05)。对照组总有效率为79.31%,研究组为96.55%,2组比较,差异有统计学意义(P<0.05)。与对照组比较,研究组甲状腺素低下、水肿与头疼的不良反应发生率均更低(P<0.05)。结论:对身高偏矮患儿采用儿童生长贴联合艾灸、运动操及饮食习惯调整相结合的方式治疗能提高身高增值与生长速度,提高疗效并减少不良反应发生,安全性高。Objective: To study the effect of Ertong Shengzhang paste combined with moxibustion, exercise and adjustment of diet habit on improving the height of children. Methods:A total of 58 cases of children with comparably short stature were enrolled as study objects,and randomly divided into the study group and the control group,29 cases in each group. The study group was given Ertong Shengzhang paste combined with moxibustion, exercise and adjustment of diet habit,and the control group was given diet guidance. Blood serum index,the increase in height and growth rate,and the effective rate and adverse reactions were compared. Results: During the first three month of intervention, there was no significant difference being found in the comparison of the increase in height and growth rate between the two groups(P>0.05);after six months of intervention,compared with those in the control group,the increase in height and growth rate in the study group were higher(P<0.05). Before intervention,there was no significant difference being found in the comparison of the levels of insulin-like growth factor-1(IGF-1) and insulin-like growth factor binding protein-3(IGFBP-3) between the two groups(P>0.05);after intervention,compared with those in the control group,the levels of IGF-1 and IGFBP-3 in the study group were both higher(P<0.05). The total effective rate was 79.31% in the control group and 96.55% in the study group,the difference being significant(P<0.05). Compared with that in the control group,the incidence of adverse reactions including hypothyroidism, edema and headache in the study group was lower(P<0.05). Conclusion: The application of Ertong Shengzhang paste combined with moxibustion, exercise and adjustment of diet habit for children with comparably short stature, can improve the increase in height and growth rate, and the curative rate, as well as reduce adverse reactions,with high safety.
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