中药治疗犬胰腺炎及作用机制研究近展  

Research advances for the treatment of canine pancreatitis with Traditional Chinese medicine and its mechanism of action

作　　者：张鹏[1,2] 郭文洁 尹星[1] 程凤琦 卢红美 张明伟 КоротковаИринаПавловна ZHANG Peng;GUO Wenjie;YIN Xing;CHENG Fengqi;LU Hongmei;ZHANG Mingwei;КоротковаИринаПавловна(College of Life Engineering,Shenyang Institute of Technology,Fushun 113122,China;Primorskaya State Academy of Agriculture,Ussuriisk 692510,Russia)

机构地区：[1]沈阳工学院生命工程学院,辽宁抚顺113122 [2]俄罗斯滨海国立农学院,俄罗斯乌苏里斯克692510

出　　处：《黑龙江畜牧兽医》2021年第5期40-43,共4页Heilongjiang Animal Science And veterinary Medicine

基　　金：辽宁省沈阳工学院新宾县特派员工作团;沈阳工学院青年骨干教师科研基金项目(QN202003)。

摘　　要：犬胰腺炎(pancreatitis)是临床常见的消化系统疾病之一,近年来该病的发病率和死亡率居高不下,但目前尚缺乏特异性和有效的治疗方法。随着国内外基础研究与临床试验的不断深入,越来越多的中草药被用于胰腺炎的治疗。因此,文章对中草药治疗胰腺炎的相关文献进行总结回顾,分别阐述中药复方及单方治疗胰腺炎的临床应用效果,同时从调节胰腺分泌功能、抗炎、抗氧化、抑制细胞内Ca2+超载、促进微循环等方面综述了中草药治疗胰腺炎的潜在作用机制,以期结合临床研究筛选出适合治疗犬胰腺炎的中草药,为临床相关治疗提供理论依据。Canine Pancreatitis is one of clinical common digestive system disease, characterized by high morbidity and mortality in recent years, however, it is lack of specificity and effective treatment. With the deepening of the basic research and clinical trials at home and abroad, a growing number of Chinese herbal medicine have been reported for the treatment of pancreatitis. Therefore, this paper summarized and reviewed the literature on treatment of pancreatitis with Chinese herbal medicine. The traditional Chinese medicine compound and monotherapy in the treatment of pancreatitis was described respectively. Meanwhile, the potential mechanism of Chinese herbal medicine in the treatment of pancreatitis was reviewed in terms of anti-inflammatory, antioxidant, inhibition of intracellular Ca2+ overload and promotion of microcirculation, in order to combine clinical research to select suitable Chinese herbal medicine for the treatment of canine pancreatitis to provide theoretical basis for clinical treatment.

关 键 词：犬 中药 胰腺炎 防治效果 机制 

分 类 号：S853.74[农业科学—临床兽医学]