ABO血型与主动脉夹层的相关性:单中心1448例回顾性队列研究  

ABO blood type and the risk of aortic dissection: a retrospective cohort study of 1448 cases in a single center

作　　者：冯鑫 夏良涛 魏翔[1] 吴志鹏 余昕宇 FENG Xin;XIA Liangtao;WEI Xiang;WU Zhipeng;YU Xinyu(Department of Cardiothoracic and Vascular Surgery,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,430030,China;Department of Neurosurgery,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology)

机构地区：[1]华中科技大学同济医学院附属同济医院心脏大血管外科,武汉430030 [2]华中科技大学同济医学院附属协和医院神经外科

出　　处：《临床心血管病杂志》2021年第2期146-150,共5页Journal of Clinical Cardiology

摘　　要：目的:探讨湖北省人群ABO血型与主动脉夹层发病的相关性。方法:回顾华中科技大学附属同济医院2011-2018年收治入院的1448例主动脉夹层患者,以武汉健康汉族人群作为对照,分析ABO血型与主动脉夹层的相关性。亚组分析ABO血型在不同亚型(Stanford分型)夹层、不同性别、不同年龄段(≥55岁及<55岁)和是否有高血压病史的主动脉夹层患者中的分布。结果:主动脉夹层患者中ABO血型分布与武汉市健康汉族人群ABO血型分布无统计学差异。亚组分析中,在<55岁的主动脉夹层患者中,AB血型患者比例高于对照组AB血型人群比例(OR 1.286,95%CI 1.011~1.638,P=0.040),其他亚组中ABO血型分布与健康人群无统计学差异。结论:湖北省人群中ABO血型不会显著影响主动脉夹层的发生。Objective: To explore the correlation between the ABO blood type and incidence of aortic dissection in the population of Hubei Province. Methods: This study included 1448 patients with aortic dissection admitted to Tongji Hospital, from 2011 to 2018. The healthy Han population in Wuhan was set as the control to analyze the correlation between ABO blood type and the risk of aortic dissection. The subgroup analyses analyzed the distribution of ABO blood type in patients with different subtypes(Stanford classification) of aortic dissection, patients of different genders, patients at different age(older or equal to 55, younger than 55), and patients with or without hypertension. Results: Our study showed that the distribution of ABO blood group in patients with aortic dissection was not statistically different from that of healthy Han population in Wuhan. In the subgroup analyses, among patients with aortic dissection under 55 years old, the proportion of patients with AB blood type was higher than that of control group(OR 1.286, 95%CI 1.011-1.638;P=0.040). Conclusion: In the population of Hubei Province, ABO blood didn’t affect the occurrence of aortic dissection significantly.

关 键 词：ABO血型系统 主动脉夹层 

分 类 号：R543[医药卫生—心血管疾病]