儿童热性惊厥临床特征分析  

Analysis of Clinical Characteristics of Febrile Seizures in Children

作　　者：刘素云[1] 陈思 张露娇 黄斌[1] 刘明[1] 程均[1] 易爱兰 罗勤[1] LIU Su-yun;CHEN Si;ZHANG Lu-jiao;HUANG Bin;LIU Ming;CHENG Jun;YI Ai-lan;LUO Qin(Department of Pediatrics,People's Hospital of Pingxiang City,Pingxiang 337000,Jiangxi,China)

机构地区：[1]江西省萍乡市人民医院儿科,江西萍乡337000

出　　处：《医学信息》2021年第8期116-118,共3页Journal of Medical Information

基　　金：江西省卫生计生委科技计划项目(编号:20177201)。

摘　　要：目的分析热性惊厥(FS)患儿临床特征。方法选取2017年6月~2018年12月我院儿科住院的FS患儿60例为研究对象,分析患儿临床特征,并对不同单次热程惊厥发作次数维生素B6含量进行分析。结果FS患儿男性多于女性,多见于3岁以内婴幼儿,以单纯性热性惊厥为主,惊厥发作时体温多>39℃,易发生于发热后24 h内,发作持续时间多<5 min内,单次热程惊厥发作次数以1次居多,无FS家族史者居多,急性上呼吸道感染是最常见病因,绝大多数患儿血常规、电解质、降钙素原、C反应蛋白、脑电图正常,其中电解质异常以低钾、低钠为主,脑电图异常多表现为尖波、慢波或尖慢波。多次发作FS患儿维生素B6含量低于总发作次数仅1次患儿[(31.97±12.15)μg/L vs(45.52±28.37)μg/L],差异有统计学意义(P<0.05)。结论FS的发生与患儿年龄、体温及呼吸道病毒感染等密切相关,多次发作FS儿童全血维生素B6含量降低,由此提示对于多次反复发作FS儿童可以适量补充维生素B6。Objective To analyze the clinical characteristics of children with febrile seizures(FS).Methods A total of 60 children with FS who were hospitalized in the Pediatrics Department of our hospital from June 2017 to December 2018 were selected as the research objects.The clinical characteristics of the children were analyzed,and the vitamin B6 content of different single heat-course seizures was analyzed.Results There were more males than females in children with FS,and it was more common in infants and young children under 3 years of age.Simple febrile seizures were the main ones.The body temperature during convulsions was more than 39℃,which tends to occur within 24 h after fever,and the duration of seizures was more than 5 within min,the number of single heat-course convulsions was mostly one,and most people without a family history of FS.Acute upper respiratory tract infection was the most common cause.The blood routine,electrolytes,procalcitonin,C-reactive protein,and electroencephalogram of the vast majority of children are normal.Among them,the electrolyte abnormalities were mainly low potassium and low sodium,and the abnormalities of the electroencephalogram were mostly sharp waves,slow waves or sharp waves.The vitamin B6 content of children with multiple episodes of FS was lower than the total number of episodes only[(31.97±12.15)μg/L vs(45.52±28.37)μg/L],the difference was statistically significant(P<0.05).Conclusion The occurrence of FS is closely related to the children's age,body temperature and respiratory virus infection.Children with multiple episodes of FS have a lower blood vitamin B6 content,which suggests that children with multiple episodes of FS can be adequately supplemented with vitamin B6.

关 键 词：热性惊厥 低钠血症 维生素B6 

分 类 号：R72[医药卫生—儿科]