大学生体力活动与血瘀质的剂量-反应关系-基于限制性立方样条模型  

Dose-response relationship between physical activity and blood stasis constitution of college students-based on restricted cubic spline model

作　　者：刘涵 朱燕波[1] 米芸 刘洋 张会 郑昆[1] 刘雯琼 马方晖 吴新瑞 LIU Han;ZHU Yanbo;MI Yun;LIU Yang;ZHANG Hui;ZHENG Kun;LIU Wenqiong;MA Fanghui;WU Xinrui(School of Management,Beijing University of Chinese Medicine,Beijing 100029,China)

机构地区：[1]北京中医药大学管理学院,北京100029

出　　处：《天津中医药》2021年第4期447-452,共6页Tianjin Journal of Traditional Chinese Medicine

基　　金：科技部基础性工作专项(2013FY114400-5)。

摘　　要：[目的]体力活动与中医体质的关系日益受到人们的关注,但有关体力活动与血瘀质的关系研究较少,且尚未有研究探索体力活动与血瘀质的剂量-反应关系。探索大学生体力活动与血瘀质的剂量-反应关系,为其科学合理的运动提供建议。[方法]采用立意抽样结合滚雪球抽样法,于2019年2—6月在大学生中施测,回收有效问卷500例,剔除不运动、分析变量缺失值者48例,452例样本纳入分析。以中医体质量表-41条目简短版(CCMQ-41)中的血瘀质亚量表测评大学生的血瘀质水平,国际体力活动问卷-短卷(IPAQ-SF)测评其总体力活动(计算每周高、中强度体力活动和日常步行能量代谢当量之和)。利用多元线性回归分析及限制性立方样条模型拟合多元线性回归模型评估体力活动与血瘀质之间的关系。[结果]452例大学生体力活动平均为每周(2020.39±1852.39)MET-min,血瘀质得分平均为(35.28±19.91)分。控制混杂因素的多元线性回归分析显示,体力活动与血瘀质之间的关系无统计学意义(线性检验:β=-0.079,t=-1.640,P=0.102);控制混杂因素的限制性立方样条拟合多元线性回归模型显示,体力活动与血瘀质存在近似“L”型的曲线(非线性检验:P-nonlinearity<0.01),血瘀质得分最低点的体力活动约为每周3000 MET-min;对于血瘀质人群来说,随着体力活动的增加,血瘀质得分降低,但当体力活动超过每周3000 MET-min,血瘀质得分基本维持在平稳水平。[结论]体力活动与血瘀质存在近似“L”型的曲线,适当增加体力活动有助于降低血瘀质得分,提升健康水平。[Objective]People pay more and more attention to the relationship between physical activity and blood stasis constitution,but the research on the relationship between physical activity and blood stasis constitution is still insufficient and no research has explored the dose-response relationship between the physical activity and blood stasis constitution.This study is to investigate the dose-response relationship between the physical activity and blood stasis constitution,and to provide suggestions scientifically and reasonably for college students.[Methods]The conceived sampling combined with snowball sampling was adopted in college students from February to June 2019.A total of 500 valid questionnaires were distributed,excluding those who did not exercise and had missing values of analysis variables,452 cases were finally included.The blood stasis constitution subscale of the 41-item short version of Constitution in Chinese Medicine Questionnaire(CCMQ-41)was used to evaluate the degree of Blood stasis constitution,the International Physical Activity Questionnaire Short Form(IPAQ-SF)was used to measure the total physical activity(Calculating the sum of weekly high and moderate-intensity physical activity and daily walking energy metabolic equivalents).Using multiple linear regression analysis and restricted cubic spline model to fit multiple linear regression model to evaluate the relationship between physical activity and Blood stasis constitution.[Results]Among 452 college students,physical activity was(2020.39±1852.3)MET-min per week,Blood stasis constitution score was(35.28±19.91).After adjusting the confounding factors,multiple linear regression showed that there was no statistical significance between physical activity and blood stasis constitution(linear test:β=-0.079,t=-1.640,P=0.102),and the restricted cubic splines showed that there is an L-shaped between physical activity and Blood stasis constitution(Non-linear test:P-nonlinearity<0.01).And the physical activity with the lowest score of blood stas

关 键 词：血瘀质 体力活动 剂量-反应关系 中医体质量表-41条目 国际体力活动问卷-短卷 

分 类 号：R2-03[医药卫生—中医学]