亚健康失眠肝郁气滞证与痰热内扰证睡眠结构的相关性研究  

Study on the correlation between the sleep structure of sub-health insomnia,liver-qi stagnation and phlegm-heat internal disturbance

作　　者：黎斌[1] 陈凌[1] 孙慧静 陈克龙[1] LI Bin;CHEN Ling;SUN Huijing;CHEN Kelong(Wenzhou Hospital of Traditional Chinese Medicine in Zhejiang Province,Wenzhou 325000,China)

机构地区：[1]浙江省温州市中医院,浙江温州325000

出　　处：《中国现代医生》2021年第8期127-130,共4页China Modern Doctor

基　　金：浙江省温州市公益性社会发展(医疗卫生)科技项目(Y20160201);浙江省中医药科技计划(2016ZA179)。

摘　　要：目的探讨亚健康失眠肝郁气滞证与痰热内扰证睡眠结构的相关性。方法选取2016年6月至2018年8月在本院门诊就诊的亚健康失眠患者,严格按照分型标准对亚健康失眠实证进行中医辨证分型,应用多导睡眠监测技术(Polysomnography,PSG)监测总睡眠时间、睡眠潜伏时间、睡眠效率、NREM期(N1期睡眠、N2期睡眠、N3期睡眠)和REM期睡眠参数。同时运用匹兹堡睡眠质量指数(Pittsburgh sleep quality index,PSQI)研究睡眠质量、入睡时间、睡眠时间、睡眠效率、睡眠障碍、催眠药物、日间功能障碍的睡眠结构,亚健康失眠实证有肝郁气滞证35例、痰热内扰证35例,对两种证型亚健康失眠的睡眠结构数据进行相关性分析。结果两组患者主观睡眠质量评估数据比较,PSQI评分总分比较,差异无统计学意义(P>0.05),PSG显示两组与常人睡眠相比具有睡眠效率较低,总睡眠时间减少、睡眠潜伏时间延长,N1期比例增多,N2、N3、REM期比例减少。组间PSG睡眠进程及睡眠结构比较,痰热内扰证组睡眠潜伏时间较长,肝郁气滞证组N2、N3期较短,差异有统计学意义(P<0.05)。结论亚健康失眠者的睡眠结构存在异常,其特征以痰热内扰证入睡困难明显,肝郁气滞证的睡眠表浅明显。Objective To explore the correlation between the sleep structure of sub-health insomnia,liver-qi stagnation syndrome and phlegm-heat internal disturbance syndrome.Methods From June 2016 to August 2018 in our hospital outpatient clinic of subhealth patients with insomnia,in strict accordance with the classification standards of subhealth insomnia empirical of traditional Chinese medicine,the application technology of Polysomnography(Polysomnography,PSG)monitoring total sleep time,sleep latency time,sleep efficiency,NREM stage(stage N1,N2 and N3 sleep sleep sleep)and a period of REM sleep parameters.At the same time using the Pittsburgh sleep quality index(Pittsburgh sleep quality index,PSQI)on sleep quality,sleep time,sleep time,sleep efficiency,sleep disorder,sleep structure of hypnotic drugs,daytime dysfunction,sub-health insomnia empirical have liver depression and qi stagnation syndrome in 35 cases,phlegm heat interference and 35 cases of two card type of sub-health insomnia sleep structure data correlation analysis.Results compared with the subjective sleep quality assessment data of the two groups,there was no statistically significant difference in the total PSQI score(P>0.05).PSG showed that compared with normal people,the two groups had lower sleep efficiency,decreased total sleep time,prolonged sleep latency,increased proportion of N1 stage,and decreased proportion of N2,N3 and REM stage.The PSG sleep process and sleep structure were compared between the two groups.The sleep latency time of the phlegm-heat internal disturbance group was longer,and the N2 and N3 stages of the liver-qi stagnation group were shorter,with statistically significant differences(P<0.05).Conclusion The sleep structure of sub-healthy insomniacs is abnormal,which is characterized by obvious difficulty in sleeping with phlegm-heat internal disturbance and obvious shallow sleep with liver depression and qi stagnation.

关 键 词：肝郁气滞 痰热内扰 亚健康失眠 睡眠监测 

分 类 号：R256.3[医药卫生—中医内科学]