短期高流量吸氧治疗慢性阻塞性肺疾病急性呼衰发作的临床分析  

Clinical Analysis of Short-term High-flow Oxygen Inhalation in the Treatment of Chronic Obstructive Pulmonary Disease with Acute Respiratory Failure

作　　者：周同鑫 ZHOU Tong-xin(Department of Respiratory Medicine,Yixing Hospital of Traditional Chinese Medicine,Yixing,Jiangsu Province,214200 China)

机构地区：[1]宜兴市中医医院呼吸内科,江苏宜兴214200

出　　处：《系统医学》2021年第5期73-75,共3页Systems Medicine

摘　　要：目的探析慢性阻塞性肺疾病急性呼衰发作患者应用短期高流量吸氧治疗的临床效果。方法选取2018年1月—2019年12月在该院治疗的134例慢性阻塞性肺疾病急性呼衰发作患者为观察对象,按照随机分组法分成对照组与实验组,每组67例。对照组患者予以常规流量吸氧治疗,实验组患者予以短期高流量吸氧治疗,对比两组患者临床效果以及治疗前后炎症标志物水平、血氧饱和度、心率、呼吸频率变化。结果实验组治疗总有效率为95.52%,明显高于对照组的83.58%,差异有统计学意义(χ^(2)=5.110,P<0.05)。实验组治疗后C反应蛋白、降钙素原水平分别为(36.34±5.16)mg/L、(0.41±0.11)ng/mL,明显低于对照组的(60.21±6.76)mg/L、(0.79±0.14)ng/mL,差异有统计学意义(P<0.05)。实验组治疗后血氧饱和度、心率、呼吸频率分别为(88.74±4.27)%、(104.14±10.26)次/min、(24.25±3.01)次/min,明显优于对照组的(83.75±4.11)%、(110.35±10.67)次/min、(32.03±3.15)次/min,差异有统计学意义(P<0.05)。结论慢性阻塞性肺疾病急性呼衰发作患者应用短期高流量吸氧治疗的临床效果十分理想,不仅可以减轻患者炎症反应,还可以改善患者呼吸功能。Objective To explore the clinical effect of short-term high-flow oxygen inhalation therapy in patients with acute respiratory failure in chronic obstructive pulmonary disease.Methods 134 patients with acute respiratory failure of chronic obstructive pulmonary disease who were treated in the hospital from January 2018 to December 2019 were selected as observation objects.According to the random grouping method,they were divided into control group and experimental group,with 67 cases in each group.Patients in the control group were treated with regular flow oxygen inhalation,and patients in the experimental group were treated with short-term high-flow oxygen inhalation.The clinical effects of the two groups of patients and the changes in inflammation marker levels,blood oxygen saturation,heart rate,and respiratory rate were compared before and after treatment.Results The total effective rate of treatment in the experimental group was 95.52%,which was significantly higher than 83.58% in the control group,the difference was statistically significant(χ^(2)=5.110,P<0.05).After treatment,the levels of C-reactive protein and procalcitonin in the experimental group were(36.34±5.16)mg/L and(0.41±0.11)ng/mL,which were significantly lower than those in the control group(60.21±6.76)mg/L and(0.79±0.14)ng/mL,the difference was statistically significant(P<0.05).The blood oxygen saturation,heart rate,and respiratory rate of the experimental group after treatment were(88.74±4.27)%,(104.14±10.26)times/min,(24.25±3.01)times/min,which were significantly better than those of the control group(83.75±4.11)%,(110.35±10.67)times/min,(32.03±3.15)times/min,the difference was statistically significant(P<0.05).Conclusion The clinical effect of short-term high-flow oxygen inhalation therapy for patients with acute respiratory failure of chronic obstructive pulmonary disease is very satisfactory.It can not only reduce the patient's inflammatory response,but also improve the patient's respiratory function.

关 键 词：慢性阻塞性肺疾病 急性呼衰发作 短期高流量吸氧 临床效果 

分 类 号：R563[医药卫生—呼吸系统]