Synthesis,Crystal Structure and Antitumor Activity of a Ca(Ⅱ) Coordination Polymer Based on 4-Acetylphenoxyacetate Ligands  

作　　者：CAO Shu-Hua TAI Xi-Shi XIN Chun-Ling 曹淑华;台夕市;辛春玲(College of Chemistry and Chemical Engineering,Weifang University,Weifang 261061,China)

机构地区：[1]College of Chemistry and Chemical Engineering,Weifang University,Weifang 261061,China

出　　处：《Chinese Journal of Structural Chemistry》2021年第3期324-328,272,共6页结构化学（英文）

基　　金：supported by the National Natural Science Foundation of China(No.21171132);the Natural Science Foundation Joint Project of Shandong Province(ZR2017LB025);Science Foundation of Weifang。

摘　　要：A novel Ca(Ⅱ) coordination polymer,[Ca L_(2)(H_(2)O)_(2)]_(n) (1,HL=4-acetylphenoxyacetic acid) has been synthesized with 4-acetylphenoxyacetic acid,Ca(ClO_4)_(2)·4H_(2)O and Na OH as raw materials.Complex 1 was characterized by elemental analysis and single-crystal X-ray diffraction analysis.The results show that the Ca(Ⅱ)ion is eight-coordinated in a distorted triangular dodecahedral geometric configuration with six carboxylate Oatoms of four L ligands and two O atoms of two coordinated water molecules.Complex 1 forms a one-dimensional chained structure by the bridging effect of carboxylate O atoms.The antitumor activity of HLligand and complex 1 has also been investigated.

关 键 词：4-acetylphenoxyacetic acid Ca(Ⅱ)coordination polymer SYNTHESIS crystal structure antitumor activity 

分 类 号：O641.4[理学—物理化学]