肺炎衣原体与中枢神经系统疾病相关性研究进展  

Research progress in the correlation of Chlamydia pneumoniae with central nervous system diseases

作　　者：袁帅 吴移谋[1] YUAN Shuai;WU Yi-mou(Institute of Pathogen Biology,University of South China,Hengyang 421001,China)

机构地区：[1]南华大学病原生物学研究所,衡阳421001

出　　处：《中国人兽共患病学报》2021年第4期368-372,377,共6页Chinese Journal of Zoonoses

基　　金：国家自然科学基金项目(No.31872643)。

摘　　要：肺炎衣原体(Chlamydia pneumoniae,Cpn)是一类具有独特双相发育周期的专性胞内寄生菌。Cpn感染过程复杂且致病类型广,除引起常见的呼吸道感染外,还可引起多个系统的慢性持续性感染。有文献报道,Cpn与中枢神经系统疾病的发生、发展密切相关。本文对Cpn与中枢神经系统疾病的相关性研究进展进行综述,为今后更合理地指导临床治疗提供重要信息。Chlamydia pneumoniae,an obligate intracellular organism,has a unique biphasic developmental cycle.Chlamydia pneumoniae infection is a complicated process with a wide range of pathogenic types.In addition to causing common respiratory tract infection,C.pneumoniae can cause chronic persistent infection of multiple systems.Chlamydia pneumoniae is closely associated with the occurrence and development of central nervous system diseases.Here,we summarize research progress in the correlation between C.pneumoniae and central nervous system diseases,and provide important information for more reasonable guidance of clinical treatment in the near future.

关 键 词：肺炎衣原体 中枢神经系统 多发性硬化 阿尔兹海默病 动脉粥样硬化性血管疾病 

分 类 号：R374[医药卫生—病原生物学]