胺碘酮治疗老年心衰并发室性心律失常的临床效果探讨  

The Clinical Effect of Amiodarone in the Treatment of Senile Heart Failure Complicated with Ventricular Arrhythmia

作　　者：辛佳音[1] 王殿栋[2] XIN Jia-yin;WANG Dian-dong(Department of Geriatrics,the First Affiliated Hospital of Baotou Medical College,Inner Mongolia University of Science and Technology,Health Care Center,Baotou,Inner Mongolia Autonomous Region,014010 China;Second Department of General Surgery,the Second Affiliated Hospital of Baotou Medical College,Inner Mongolia University of Science and Technology,Baotou,Inner Mongolia Autonomous Region,014030 China)

机构地区：[1]内蒙古科技大学包头医学院第一附属医院医疗保健中心老年病科,内蒙古包头014010 [2]内蒙古科技大学包头医学院第二附属医院普外二科,内蒙古包头014030

出　　处：《中外医疗》2021年第8期103-105,123,共4页China & Foreign Medical Treatment

摘　　要：目的探讨胺碘酮治疗老年心衰并发室性心律失常的临床效果。方法方便选择该院2018年1月—2019年12月收治的90例心衰并发室性心律失常老年患者进行研究,使用随机数表法将其分为对照组和研究组,每组45例。对照组患者给予维持水电解质与酸碱平衡、扩张血管、利尿等常规治疗,研究组在对照组基础上加用胺碘酮治疗,比较治疗前后两组体内脑钠肽前提浓度、左室射血分数和心率,两组治疗后血压、QTc以及临床治疗效果。结果治疗前两组体内脑钠肽前提浓度、左室射血分数和心率差异无统计学意义(P>0.05);治疗后两组各项指标明显改善,且研究组优于对照组,差异有统计学意义(P<0.05);组间SBP和DBP差异无统计学意义(P>0.05);研究组QTc明显长于对照组,差异有统计学意义(P<0.05);研究组治疗总有效率为95.56%,明显高于对照组,差异有统计学意义(χ^(2)=4.050,P=0.044<0.05)。结论对老年心衰并发室性心律失常患者,在实施常规治疗基础上加用胺碘酮治疗,利于改善患者心脏状况,同时该药物对患者血压影响较小,药物使用安全性高,能够提升临床治疗效果。Objective To explore the clinical effect of amiodarone in the treatment of senile heart failure complicated with ventricular arrhythmia;Methods convenient Selected 90 elderly patients with heart failure and ventricular arrhythmia admitted to the hospital from January 2018 to December 2019 for research.They were divided into a control group and a study group using a random number table method,with 45 cases in each group.Patients in the control group were given conventional treatments such as maintenance of water,electrolyte and acid-base balance,blood vessel dilation,and diuresis.The study group was treated with amiodarone on the basis of the control group.The pre-brain natriuretic peptide concentration and left ventricular ejection were compared before and after treatment.Score and heart rate,blood pressure,QTc and clinical treatment effect after treatment in the two groups.Results Before treatment,there was no statistically significant difference in brain natriuretic peptide concentration,left ventricular ejection fraction,and heart rate between the two groups(P>0.05);after treatment,the indicators of the two groups were significantly improved,and the study group was better than the control group.There were differences statistical significance(P<0.05);There was no significant difference in SBP and DBP between groups(P>0.05);QTc of the study group was significantly longer than that of the control group,and the difference was statistically significant(P<0.05);the total effective rate of treatment in the study group It was 95.56%,which was significantly higher than the control group,and the difference was statistically significant(χ^(2)=4.050,P=0.044<0.05).Conclusion For elderly patients with heart failure complicated with ventricular arrhythmia,add amidoiodine on the basis of conventional treatment Ketone therapy is beneficial to improve the patient's heart condition.At the same time,the drug has little effect on the blood pressure of the patient,and the drug is safe to use,which can improve the clinical treatmen

关 键 词：胺碘酮 老年心衰 室性心律失常 血压 体内脑钠肽前提浓度 

分 类 号：R4[医药卫生—临床医学]