海昆肾喜胶囊联合血管紧张素转换酶抑制剂治疗慢性肾小球肾炎的临床疗效  

Clinical effect of Haikun Shenxi capsule combined with angiotensinconverting enzyme inhibitor in the treatment of chronic glomerulonephritis

作　　者：张俊 刘永光[2] Zhang Jun;Liu Yongguang

机构地区：[1]广东省广州市韦士泰血液透析所,广东广州511431 [2]南方医科大学珠江医院,广东广州510000

出　　处：《中医临床研究》2021年第3期123-124,共2页Clinical Journal Of Chinese Medicine

摘　　要：目的:探究海昆肾喜胶囊联合血管紧张素转换酶抑制剂治疗慢性肾小球肾炎的临床疗效。方法:选取2013年11月-2016年11月于南方医科大学珠江医院接受治疗的122例慢性肾小球肾炎患者作为研究对象。基于随机数字表法均分成对照组与观察组两组,每组61例。对照组予以常规治疗,观察组则给予海昆肾喜胶囊联合血管紧张素转换酶抑制剂治疗,分析比对两组队形临床治疗效果。结果:治疗前,两组对象血肌酐(Serum Creatinine,Scr)、总胆固醇(Total Cholesterol,TC)、三酰甘油(Triglyceride,TG)和24 h尿蛋白水平对比差异无统计学意义(P>0.05);治疗后,观察组Scr、TC、TG和24 h尿蛋白水平相较于参照组均呈现明显优越性,各项对比结果数据差异均有统计学意义(P<0.05)。结论:应用海昆肾喜胶囊联合血管紧张素转换酶抑制剂治疗慢性肾小球肾炎疗效显著,能有效改善患者临床病症指标,值得进一步推广。Objective:To explore the clinical efficacy of Haikun Shenxi capsules(海昆肾喜胶囊)combined with angiotensinconverting enzyme inhibitors in the treatment of chronic glomerulonephritis.Methods:Based on the study period from November 2013 to November 2016,122 patients with chronic glomerulonephritis who were treated in Wei Stern Hemodialysis Institute,Guangzhou city,Guangdong Province were selected as the research subjects.The control and the observation groups were equally divided based on the random number table method,with 61 cases in each group.The control group was given conventional treatment,and the observation group was given Haikun Shenxi capsule combined with angiotensin-converting enzyme inhibitor.The clinical treatment effect of the two groups was analyzed and compared.Results:Before treatment,Scr,TC,TG and 24h urine protein levels of the two groups of subjects did not show a significant difference(P>0.05).After treatment,Scr,TC,TG and 24h urine protein levels of the observation group were compared with those of the control group.The data of each comparison result were significantly different(P<0.05).Conclusion:The application of Haikun Shenxi capsules combined with angiotensin-converting enzyme inhibitors has significant effects in the treatment of chronic glomerulonephritis,it can effectively relieve the clinical symptoms of patients,and is worth further promotion.

关 键 词：慢性肾小球 肾炎 海昆肾喜胶囊 血管紧张素转换酶抑制剂 疗效 

分 类 号：R692.3[医药卫生—泌尿科学]