活血利水汤联合西药治疗对原发性肾病综合征患者中医证候积分及肾功能指标的影响  

The effects of the Huoxue Lishui decoction plus Western medicine on TCM syndrome score and renal function in patients with primary nephrotic syndrome

作　　者：郭志杰 倪斌 Guo Zhijie

机构地区：[1]湖北省天门市中医医院,湖北天门431700

出　　处：《中医临床研究》2021年第5期63-65,共3页Clinical Journal Of Chinese Medicine

摘　　要：目的:探究活血利水汤联合西药治疗对原发性肾病综合征(Primary Nephrotic Syndrome,PNS)患者中医证候积分及肾功能的影响。方法:选取2017年9月-2019年11月于我院接受治疗的PNS患者82例,按随机数字表法分为两组,各41例。对照组口服泼尼松治疗,观察组在上述治疗基础上联合活血利水汤治疗。对比两组总有效率、治疗前后中医证候积分及肾功能各指标水平。结果:观察组总有效率高于对照组,中医证候积分低于对照组,差异均有统计学意义(P<0.05);观察组的肌酐、胆固醇及尿蛋白定量水平低于对照组,血浆白蛋白水平高于对照组,差异有统计学意义(P<0.05)。结论:活血利水汤联合西药在PNS治疗中疗效确切,可降低中医证候积分,改善肾功能指标,有助于稳定病情,值得推广应用。Objective:To explore the effects of the Huoxue Lishui decoction(活血利水汤)plus Western medicine on TCM syndromes score and renal function in patients with primary nephrotic syndrome.Methods:82 cases were selected and divided into two groups according to the random number table method,with 41 cases in each group.The control group was treated with oral prednisone,the observation group was treated with the Huoxue Lishui decoction more.Results:The total efficiency in the observation group was higher than that in the control group,and the TCM syndrome score was lower than the control group.The differences were all statistically significant(P<0.05).The creatinine,cholesterol and urinary protein quantification levels in the observation group were lower than those in the control group.The albumin level was higher than the control group,and the difference was statistically significant(P<0.05).Conclusion:The Huoxue Lishui decoction plus Western medicine shows a definite effect on PNS.It can reduce TCM syndrome scores,ameliorate renal function indexes,help to stabilize the condition,and is worthy of popularization and application.

关 键 词：原发性肾病综合征 活血利水汤 泼尼松 肾功能 

分 类 号：R692[医药卫生—泌尿科学]