马鞍山市新型冠状病毒肺炎病例特征及病毒检测分析  

Analysis of characteristics and virus detection of COVID-19 cases in Ma′anshan

作　　者：洪颖[1] 杨锟[2] 王利[1] 项可霞[1] 江良梁[3] 沈志斌[1] 陈谨[1] 罗颖 王蓉 杨晨 徐凌[1] 田芳[1] 陈道利[1] 陈健 Hong Ying;Yang Kun;Wang Li;Xiang Kexia;Jiang Liangliang;Shen Zhibin;Chen Jin;Luo Ying;Wang Rong;Yang Chen;Xu Ling;Tian Fang;Chen Daoli;Chen Jian(Microbiological Laboratory of Ma′anshan Center for Disease Control and Prevention,Ma′anshan 243000,China;Emergency Management Office of Ma′anshan Center for Disease Control and Prevention,Ma′anshan 243000,China;Immunoprophylaxis Section of Ma′anshan Center for Disease Control and Prevention,Ma′anshan 243000,China;Ma′anshan Center for Disease Control and Prevention,Ma′anshan 243000,China)

机构地区：[1]马鞍山市疾病预防控制中心微生物检验科,243000 [2]马鞍山市疾病预防控制中心应急办,243000 [3]马鞍山市疾病预防控制中心免疫预防科,243000 [4]马鞍山市疾病预防控制中心,243000

出　　处：《中华实验和临床病毒学杂志》2021年第1期11-14,共4页Chinese Journal of Experimental and Clinical Virology

摘　　要：目的了解马鞍山市新型冠状病毒肺炎的基本特征及不同标本的病毒携带情况。方法应用描述性流行病学方法分析马鞍山市新型冠状病毒感染者的三间分布情况,采用实时荧光RT-PCR方法检测痰液和(或)咽拭子中新型冠状病毒核酸,使用EXCEL和SPSS 20.0对数据进行分析,率的比较使用χ^(2)检验,以P<0.05为差异有统计学意义。结果截至2020年3月14日马鞍山市累计报告确诊病例38例,无死亡病例,另发现无症状感染者11例;新型冠状病毒感染者最早发现于1月23日,最迟于2月20日,已持续23日未发现新增感染者;77.55%(38/49)的感染者分布于和县;1447例研究对象中,女性的阳性率4.50%(27/600),男性为2.60%(22/847)(χ^(2)=3.886,P=0.049);2019-nCoV感染者最小年龄为4岁,最大为85岁,中位年龄为46岁,年龄组间差异无统计学意义(χ^(2)=10.675,P=0.058);49例感染者中武汉返乡人员为20例(40.82%),本地感染24例(48.98%),非武汉返乡人员5例(10.20%);首次新型冠状病毒核酸检测阳性者中,痰液的阳性率(100%,36/36)高于咽拭子(77.78%,28/36),且差异具有统计学意义(χ^(2)=6.125,P<0.05)。结论马鞍山市新型冠状病毒感染者集中于和县,痰液标本有利于新型冠状病毒的检出。Objective To understand the basic characteristics of COVID-19 cases and the virus carrying status of different samples in Ma′anshan.Methods Descriptive epidemiological method was used to describe the distribution of 2019-nCoV infections in Ma′anshan.Real-time fluorescence RT-PCR was used to detect 2019-nCoV nucleic acid in sputum and/or throat swabs.Data was analyzed by EXCEL and SPSS 20.0.P<0.05 was considered to be statistically significant by usingχ^(2) test.Results Until 14 March 2020,38 confirmed cases and no death had been reported in Ma′anshan,there were also 11 asymptomatic infections.2019-nCoV infection was first detected on January 23,and the last was on February 20.No new infections have been found for 23 consecutive days until March 14;77.55%(38/49)of the infections were in He county.Among the 1447 subjects,the positive rate was 4.50%(27/600)in females and 2.60%(22/847)in males(χ^(2)=3.886,P=0.049).The minimum age of the infections was 4 years and the maximum was 85.There was no significant difference between age groups(χ^(2)=10.675,P=0.058).Among the 49 infections,20 of them(40.82%)were from Wuhan,24(48.98%)were locally infected,and 5(10.20%)were imported from other places.For the first positive infections,the positive rate of sputum(100%,36/36)was higher than the throat swab(77.78%,28/36),and the difference was statistically significant(χ^(2)=6.125,P<0.05).Conclusions In Ma′anshan,2019-nCoV infections were concentrated in He county,sputum was beneficial to the detection of 2019-nCoV.

关 键 词：新型冠状病毒肺炎 新型冠状病毒 痰液 咽拭子 

分 类 号：R563.1[医药卫生—呼吸系统]