人工脑膜应用对去骨瓣减压术后颅内感染风险的影响  

Influence of artificial dura mater application on the risk of intracranial infection following decompressive craniectomy

作　　者：陈子建 朱园润 杨小锋[2] CHEN Zijian;ZHU Yuanrun;YANG Xiaofeng(Zhejiang University School of Medicine,310058,China)

机构地区：[1]浙江大学医学院第一临床医学院,杭州310058 [2]浙江大学医学院附属第一医院急诊创伤中心

出　　处：《浙江创伤外科》2021年第2期199-201,共3页Zhejiang Journal of Traumatic Surgery

摘　　要：目的分析人工脑膜的应用对去骨瓣减压术患者术后颅内感染风险的影响。方法本研究为单中心、回顾性队列研究,纳入2019年6月至2020年6月于浙江大学医学院附属第一医院神经外科行去骨瓣减压术的患者57例,依据是否应用人工脑膜分为两组,比较术后颅内感染的发生率。结果应用人工脑膜的去骨瓣减压术患者(17例)均无术后脑脊液漏发生;与未应用者(40例)相比,其年龄、性别、急诊手术占比、术前气管插管或切开比例、术前GCS评分、术前诊断、手术持续时间、颅内压监护或脑室外引流比例、术后ICU天数、术后气管插管或切开天数以及术后颅内感染率均无统计学差异。结论人工脑膜的应用在不伴脑脊液漏的情况下不增加去骨瓣减压术后颅内感染的风险。Objective To analyze the influence of artificial dura mater on the risk of intracranial infection following decompressive craniectomy. Methods This is a single-center and retrospective cohort study. A total of 57 patients underwent decompressive craniectomy from June 2019 to June 2020 in our hospital were included. These patients were divided into two groups according to whether artificial dura mater was applied in the surgery, and the intracranial infection rate was compared. Results There were 17 patients with artificial dura mater application and none of them had suffered cerebrospinal fluid(CSF) leak. Comparing with those without artificial dura mater(40 patients), no statistical difference of age, gender, emergent operation ratio, pre-operation artificial airway ratio, pre-operation GCS, diagnosis composition, operation duration, external ventricular drain ratio, post-operation ICU duration, artificial airway duration or intracranial infection rate were found. Conclusion For patients without CSF leak, artificial dura mater does not increase the risk of intracranial infection of decompressive craniectomy.

关 键 词：创伤性脑损伤 去骨瓣减压术 人工脑膜 脑脊液漏 颅内感染 

分 类 号：R651.1[医药卫生—外科学]