HA/β-TCP支架材料的研究进展  

Research progress of HA/β-TCP scaffolds

作　　者：刘健鑫 叶尔盼·艾力卡木 郭连阳 高懿 刘家伶 廖文 Liu Jianxin;Erpan·Alkam;Guo Lianyang;Gao Yi;Liu Jialing;Liao Wen(West China School of Stomatology,Sichuan University;Department of Orthodontic,West China.Hospital of Stomatology,Sichuan University;State Key Laboratory of Oral Diseases,Sichuan University;National Clinical Research Center for Oral Diseases,Sichuan University,Chengdu Sichuan,610000,China)

机构地区：[1]四川大学华西口腔医学院 [2]四川大学华西口腔医院正畸科 [3]四川大学口腔疾病研究国家重点实验室 [4]四川大学国家口腔疾病临床医学研究中心,四川成都610000

出　　处：《生物骨科材料与临床研究》2021年第2期67-71,共5页Orthopaedic Biomechanics Materials and Clinical Study

基　　金：国家自然科学基金(31600752);四川大学-泸州市人民政府战略合作项目(2018CDLZ-14)。

摘　　要：随着骨修复材料需求的增多,HA/β-TCP复合支架作为一种兼具良好的生物相容性、生物降解性、骨传导性以及骨诱导性的生物材料受到了人们的广泛关注。本文关注于web of science上的相关文献,主要论述以下几个方面内容:HA/β-TCP组成比例对复合支架的性能影响;HA/β-TCP复合支架与其他主流材料的复合;新制作工艺的出现与结构改进。在技术推进和研究深入的背景下,对作为骨修复工程中较为理想的生物材料HA/β-TCP复合支架的发展现状进行介绍。With the increasing demand on bone repair materials,as a kind of biomaterials with good biocompatibility,biodegradability,bone conductivity and bone inductivity,HA/β-TCP composite scaffold has been given high expectations.In this paper,we collected related articles included on web of science,focusing on several parts:The effect of HA/β-TCP composition ratio on the performance of this composite scaffold;the combination of HA/β-TCP scaffold with other mainstream materials;the appearance of new fabrication technology and structure improvement.As a result of technology advancement and in-depth researches,HA/β-TCP composite scaffold has been refined as an ideal biomaterial in bone repair engineering,whose optimization and application have been reviewed in this paper.

关 键 词：骨修复材料 生物材料 HA/β-TCP复合支架 

分 类 号：R318[医药卫生—生物医学工程]