山楂酸药理作用及其机制的研究进展  

Research advances on pharmacological effects and mechanisms of maslinic acid

作　　者：李宣 何迎春[1] 周芳亮[1] Xuan Li;Ying-chun He;Fang-liang Zhou(Hunan Provincial Key Laboratory for the Prevention and Treatment of Ophthalmology and Otolaryngology Diseases with Traditional Chinese Medicine,Hunan University of Chinese Medicine,Changsha,Hunan 410208,China)

机构地区：[1]湖南中医药大学医学院,湖南长沙410208

出　　处：《中国现代医学杂志》2021年第8期49-53,共5页China Journal of Modern Medicine

基　　金：湖南省自然科学基金(No:2017JJ3246);湖南中医药大学大学生研究性学习与创新性实验计划项目。

摘　　要：山楂酸是一种五环三萜酸,存在于枇杷叶、油橄榄和山楂等多种天然植物中,具有抗肿瘤、降血糖、抗炎、抑制寄生虫等多种生物学活性。该文就山楂酸的药理作用及其机制的研究现状进行综述,为进一步开发利用山楂酸提供理论基础。Maslinic acid(MA) is a pentacyclic triterpene acid that is present in numerous dietary plants such as folium eriobotryae, olive, hawthorn and so on. It has many biological activities including anti-tumor,hypoglycemic, anti-inflammation and anti-parasitic effects. In order to provide a theoretical basis for the further development and utilization of maslinic acid, this article reviews the research status of the pharmacological effects and mechanisms of maslinic acid.

关 键 词：山楂酸/山楂属 药理作用 抗肿瘤药 降血糖药 

分 类 号：R285.5[医药卫生—中药学]