食管闭锁重建术后食管功能评估的现状与发展  

Current status and future development of esophageal function after a reconstruction of esophageal atresia

作　　者：林阳文(综述) 江怡(审校) 王俊(审校)[1] Lin Yangwen;Jiang Yi;Wang Jun(Department of Pediatric Surgery,Affiliated Xinhua Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200092,China)

机构地区：[1]上海交通大学医学院附属新华医院小儿外科,上海市200092

出　　处：《临床小儿外科杂志》2021年第4期388-392,共5页Journal of Clinical Pediatric Surgery

基　　金：上海市科委2019年度“科技创新行动计划”生物医药领域科技支撑项目指《长段缺失型食管闭锁“自吻合”装置的研发》(19441905500);上海市转化医学协同创新中心《复合力作用食管延长吻合装置的研发》(TM201910)。

摘　　要：食管功能异常是食管闭锁(esophageal atresia,EA)患者食管重建术后常见的问题。术后食管功能的恢复或改善对患者生活质量至关重要。随着近年国内EA治愈率的提高,人们开始关注患者术后并发症情况,尤其是术后食管功能的恢复问题。食管功能异常的影响因素众多,不仅与术前既有食管状态有关,同时与手术创伤、术后并发症及形态亦有很大关系。但目前术后食管功能评价体系仍不健全,没有形成有效合理的治疗策略。本文通过总结国内外EA术后食管功能异常的病理生理基础、临床表现、评估手段及治疗经验等,进一步明确食管功能异常相关因素,为探索有效完整且公认的评价体系及治疗策略提供参考依据。Esophageal dysfunction is a common problem after esophageal reconstruction in children with esophageal atresia.Recovery or improvement of postoperative esophageal function is critical for quality-of-life.With the improved cure rate of esophageal atresia in recent years,pediatric surgeons have begun to focus upon the complications and recovery of esophageal function.Many influencing factors of esophageal dysfunction are not only related with preoperative esophageal status,but also surgical trauma,postoperative complications and morphologies.Postoperative evaluation system of esophageal function has remained imperfect and no effective and rational treatment strategy is available.This review intends to summarize the pathophysiological fundamentals,clinical manifestations,assessment methods and treatment experiences of esophageal dysfunction.And the authors try to clarify the factors related with esophageal dysfunction and provide rationales for exploring effective and complete evaluation systems and treatment strategies.

关 键 词：食管闭锁/外科学 食管功能 胃食管反流 

分 类 号：R726[医药卫生—儿科] R571[医药卫生—临床医学]