自拟补气通秘方治疗老年气阴两虚型便秘25例临床观察  

Clinical Observation on the Treatment of 25 Cases of Senile Constipation with Deficiency of Qi and Yin by Self-made Recipe

作　　者：潘慧[1] 姚宏健 常为伟[1] 李阳 陈淑君[1] 刘佃温[3] 刘世举[3] PAN Hui;YAO Hongjian;CHANG Weiwei;LI Yang;CHEN Shujun;LIU Dianwen;LIU Shiju(The First Affiliated Hospital to Henan University of Traditional Chinese Medicine,Zhengzhou 450000,China;The Huanghe Central Hospital,Zhengzhou 450000,China;The Third Affiliated Hospital to Henan University of Traditional Chinese Medicine,Zhengzhou 450000,China)

机构地区：[1]河南中医药大学第一附属医院,河南郑州450000 [2]黄河中心医院,河南郑州450000 [3]河南中医药大学第三附属医院,河南郑州450000

出　　处：《中国民族民间医药》2021年第7期114-118,共5页Chinese Journal of Ethnomedicine and Ethnopharmacy

基　　金：全国中医临床特色技术传承骨干人才培训项目(国中医药人教函[2019]36);河南省科技攻关(162102310107);河南省中医药科学研究专项课题(2015ZY2057)。

摘　　要：目的:观察自拟补气通秘方加减治疗气阴两虚证老年便秘的临床疗效及对患者血清SP、VIP和NO水平的影响。方法:将50例老年患者且诊断为气阴两虚证者随机分为对照组和观察组,每组25例。对照组给予芪蓉润肠口服液口服治疗;观察组给予自拟补气通秘方加减口服治疗。治疗1月后观察两组排便顺畅度,便后汗出气喘、粪便性状和腹胀腹痛等各项临床症状的改善情况及治疗前后血清SP、VIP和NO水平的变化。结果:治疗后观察组排便顺畅度,便后汗出气喘、粪便性状和腹胀腹痛等各项临床症状改善均优于对照组(P<0.05);同时观察组整体有效率优于对照组(P<0.05);观察组SP升高,VIP、NO降低,显著优于对照组(P<0.05)。结论:自拟补气通秘方加减治疗老年气阴两虚证便秘疗效显著,可升高血清SP,降低VIP、NO并有效缓解患者排便不顺畅,便后汗出气喘,粪便干结和腹胀腹痛等症状,具有一定的临床价值。Objective To observe the clinical efficacy of self-made Buqi Tongmi Decoction in treating constipation in the elderly with deficiency of both Qi and Yin,and its effect on the serum levels of SP,VIP and NO.Methods Fifty elderly patients who were diagnosed with Qi and Yin deficiency were randomly divided into 2 groups,25 cases in each group.The control group was given Qirong Runchang Oral Liquid for oral treatment;the observation group was given the self-made Buqi Tongmi Recipe plus or minus oral treatment.After 1 month of treatment,the two groups of patients were observed to observe the smoothness of defecation,sweating and wheezing after defecation,the improvement of various clinical symptoms such as stool characteristics,bloating and abdominal pain,and the changes of serum SP,VIP and NO levels before and after treatment.Results After treatment,the observation group patients had better defecation smoothness,sweating and wheezing after defecation,fecal characteristics,abdominal distension and abdominal pain and other clinical symptoms improved better than the control group(P<0.05);at the same time,the observation group’s overall effective rate was better than the control group(P<0.05);SP increased in observation group,VIP and NO decreased,compared with control group,it was better than control group(P<0.05).Conclusion The self-made Buqi Tongmi Recipe has a significant effect on the treatment of constipation due to deficiency of both Qi and Yin in the elderly.It can increase serum SP,decrease VIP and NO,and effectively relieve patients with unsmooth defecation,sweating and asthma after stool,dry stool and abdominal distension and abdominal pain Such symptoms have certain clinical value.

关 键 词：老年便秘 自拟补气通秘方 气阴两虚证 临床观察 

分 类 号：R256.35[医药卫生—中医内科学]