特发性正常颅压脑积液患者的听力研究  

Hearing Loss in Patients with Idiopathic Normal Pressure Hydrocephalus

作　　者：王轶[1] 栾岚[1] 魏俊吉[2] 高志强[1] Wang Yi;Luan Lan;Wei JunJi(Department of Otolaryngology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100730,China)

机构地区：[1]中国医学科学院/北京协和医学院北京协和医院耳鼻喉科,100730 [2]中国医学科学院/北京协和医学院北京协和医院神经外科,100730

出　　处：《医学研究杂志》2021年第3期84-87,共4页Journal of Medical Research

摘　　要：目的调查iNPH患者分流术前听力减退的发生率、类型和严重程度。方法对确诊iNPH的患者组和年龄、性别匹配的健康对照组的听力减退的发生率、类型和严重程度进行了横断面对照研究。比较了患者组和对照组纯音测听传统频率范围的听阈、扩展高频的听阈、鼓室压曲线。结果iNPH患者30例和年龄、性别匹配的对照组30例入选。患者组听力损失的发生率明显高于对照组(63%vs 27%,P<0.05)。除16kHz外,iNPH组各频率听阈均显著高于对照组。听力损失为典型的感音神经性聋,以轻~中度为主。结论iNPH患者听力损失较常见。提醒神经内、外科医生应该注意检测iNPH患者的听力。Objective To investigate the prevalence,type and severity of hearing loss in iNPH patients before shunting.Methods A comparative cross-sectional study on the prevalence,type and severity of hearing loss in diagnosed iNPH patients and healthy controls matched for age and gender was performed.Conventional pure tone audiometry,extended high frequency audiometry and tympanometry were recorded in iNPH patients pre-shunt placement and in controls.Results Thirty patients fulfilled the diagnostic criteria of iNPH and 30 controls were enrolled.The prevalence of hearing loss in was significantly higher than the controls(63%vs 27%,P<0.05).The hearing thresholds of the iNPH group were significantly higher than the control group at each frequency except 16kHz.The hearing loss of the iNPH patients was typically sensorineural,most of them were of mild and moderate degree.Conclusion Hearing loss was common in iNPH patients.Doctors should pay attention to hearing in addition to the three main symptoms of iNPH in order to not miss hearing loss in patients with iNPH.

关 键 词：听力减退 特发性正常颅压脑积液 脑脊液 内淋巴积液 外淋巴水肿 

分 类 号：R651[医药卫生—外科学]