血管内光学相干层析成像中的冠状动脉支架重建  

Coronary Stent Reconstruction in Intravascular Optical Coherence Tomography

作　　者：刘铁根 陶魁园 丁振扬 刘琨 江俊峰 卢瑞祥 黄进宇[3] 周亮[3] 高贝贝[3] 童国新[3] 曹苹 邓沛涛 徐克永 彭成庆 万通 欧桂康 Liu Tiegen;Tao Kuiyuan;Ding Zhenyang;Liu Kun;Jiang Junfeng;Lu Ruixiang;Huang Jinyu;Zhou Liang;Gao Beibei;Tong Guoxin;Cao Ping;Deng Peitao;Xu Keyong;Peng Chengqing;Wan Tong;Ou Guikang(School of Precision Instrument and Opto-Electronics Engineering,Tianjin University,Key Laboratory of the Ministry of Education on Optoelectronic Information Technology,Tianjin Optical Fiber Sensing Engineering Center,Tianjin 300072,China;Shenzhen Academy of Metrology and Quality Inspection,Shenzhen,Guangdong 518055,China;Hangzhou First People′s Hospital,Hangzhou,Zhejiang 310006,China;Shenzhen Testing Center of Medical Devices,Shenzhen,Guangdong 518055,China;Nanjing Forssmann Medical Technology Co.,Ltd.,Nanjing,Jiangsu 210041,China)

机构地区：[1]天津大学精密仪器与光电子工程学院光电信息技术教育部重点实验室天津市光纤传感工程中心,天津300072 [2]深圳市计量质量研究院,广东深圳518055 [3]杭州市第一人民医院,浙江杭州310006 [4]深圳市医疗器械检测中心,广东深圳518055 [5]南京沃福曼医疗科技有限公司,江苏南京210041

出　　处：《光学学报》2021年第4期160-167,共8页Acta Optica Sinica

基　　金：国家自然科学基金(61975147,61635008,61735011,61505138);国家重点研发计划(2019YFC0120701,2019YFC0120703)。

摘　　要：冠状动脉支架置入已经成为冠状动脉粥样硬化性心脏病的重要治疗手段。药物洗脱冠状动脉支架断裂(CSF)的识别与检测是目前的难点问题。血管内光学相干层析成像(IVOCT)系统以其极高的成像分辨率在CSF识别与检测方面具有独特优势。本文提出了一种在IVOCT中对冠状动脉支架精准重建的方法。该方法利用金属支架具有成像阴影这一特征,在血管边界分割后,将支架及其一定深度阴影的强度值进行累加生成一维数组,然后将一维数组按照回撤次序排列形成支架展开图像。与三维成像、纵切图像等支架重建方法相比,所提方法不仅可以保持支架的整体结构,而且避免了对操作人员空间想象力的要求。本文利用所提重建方法定量识别和分析了CSF,该方法可针对不同的支架结构选择不同的IVOCT成像参数。At present,coronary stent implantation has become an important treatment for coronary atherosclerotic heart disease.It is difficult to identify and detect drug-eluting coronary stent fracture(CSF).Intravascular optical coherence tomography(IVOCT)has unique advantages in CSF identification and detection due to its extremely high imaging resolution.Given the above situation,we propose an accurate reconstruction method of coronary stents in IVOCT.On the basis of the fact that the metal stents have imaging shadows,after the vessel boundaries are segmented,the intensity values of a stent and its shadows at a certain depth are accumulated to generate a one-dimensional array.Then,the array is arranged according to the pullback order to produce a stent reconstruction image.Compared with other stent reconstruction methods(such as three-dimensional imaging,longitudinal image cutting),the proposed method can not only maintain the overall structure of the stents but also avoid the requirement of spatial imagination on the operators.In conclusion,the method proposed in this paper can quantitatively identify and analyze CSF,providing different IVOCT imaging parameters for different stent structures.

关 键 词：医用光学 相干成像 光学相干层析成像 血管内光学相干层析成像 支架重建 

分 类 号：TN29[电子电信—物理电子学]